ChemicalBook > CAS DataBase List > Eliglustat

Eliglustat

Product Name
Eliglustat
CAS No.
491833-29-5
Chemical Name
Eliglustat
Synonyms
CS-1540;Genz 99067;Eliglustat;Eliglustate;Elli Gustast;Eliglustat Free Base;Eliglustat(Genz-99067);Eliglustat(GENZ 112638);Eliglustat, 10 mM in DMSO;GENZ-99067; GENZ99067; GENZ 99067
CBNumber
CB52627796
Molecular Formula
C23H36N2O4
Formula Weight
404.54
MOL File
491833-29-5.mol
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Eliglustat Property

Melting point:
87-92°C
Boiling point:
615.5±55.0 °C(Predicted)
Density 
1.123±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.45±0.20(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P331Do NOT induce vomiting.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E508030
Product name
Eliglustat
Packaging
5mg
Price
$70
Updated
2021/12/16
TRC
Product number
E508030
Product name
Eliglustat
Packaging
10mg
Price
$95
Updated
2021/12/16
AK Scientific
Product number
0516DB
Product name
Eliglustat
Packaging
1mg
Price
$122
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158477
Product name
N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide
Packaging
10mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD158477
Product name
N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide
Packaging
25mg
Price
$125
Updated
2021/12/16
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Eliglustat Chemical Properties,Usage,Production

Uses

Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.

Definition

ChEBI: A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltr nsferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.

Biological Activity

Eliglust at is a potent and selctive glucosylceramide synthase inhibitor approved for treatment of type 1 Gaucher disease.

Eliglustat Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Eliglustat manufacturers

Career Henan Chemical Co
Product
Eliglustat 491833-29-5
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

491833-29-5, EliglustatRelated Search:


  • Eliglustat
  • Genz 99067
  • N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide
  • GENZ-99067;GENZ99067;GENZ 99067;ELIGLUSTAT TARTRATE;GENZ-112638
  • N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1- pyrrolidinyl)-2-propanyl]octanamide
  • Eliglustat(Genz-99067)
  • Eliglustat(GENZ 112638)
  • GENZ-99067; GENZ99067; GENZ 99067
  • N-[(1r,2r)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide
  • CS-1540
  • Elli Gustast
  • Octanamide, N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-
  • Eliglustat (GENZ-112638, Genz 99067, Cerdelga)
  • EliglustatQ: What is Eliglustat Q: What is the CAS Number of Eliglustat Q: What is the storage condition of Eliglustat Q: What are the applications of Eliglustat
  • Eliglustate
  • Eliglustat Free Base
  • N-((1R,2R)-1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide
  • Eliglustat, 10 mM in DMSO
  • 491833-29-5