ChemicalBook > CAS DataBase List > TBPB
TBPB
- Product Name
- TBPB
- CAS No.
- 634616-95-8
- Chemical Name
- TBPB
- Synonyms
- TBPB(1%EA);TBPB, 10 mM in DMSO;1-(1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one;1-(1'-(2-Methylbenzyl)-[1,4'-bipiperidin]-4-yl)-1H-benzo[d]imidazol-2(3H)-one;1,3-Dihydro-1-[1'-[(2-methylphenyl)methyl][1,4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1'-[(2-Methylphenyl)Methyl][1,4'-bipiperidin]-4-yl]-;1-{1'-[(2-methylphenyl)methyl]-[1,4'-bipiperidin]-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
- CBNumber
- CB52628445
- Molecular Formula
- C25H32N4O
- Formula Weight
- 404.55
- MOL File
- 634616-95-8.mol
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TBPB Property
- Density
- 1.193±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble5mg/mL (clear solution; warmed)
- pka
- 12.04±0.30(Predicted)
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0453
- Product name
- TBPB
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $102
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0453
- Product name
- TBPB
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $436
- Updated
- 2022/05/15
Cayman Chemical
- Product number
- 22943
- Product name
- TBPB
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22943
- Product name
- TBPB
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 22943
- Product name
- TBPB
- Packaging
- 10mg
- Price
- $163
- Updated
- 2024/03/01
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TBPB Chemical Properties,Usage,Production
Uses
TBPB is an allosteric M1 muscarinic acetylcholine receptor activator that regulates amyloid processing and produces antipsychotic-like activity in rats.
Biological Activity
TBPB is a highly selective Muscarinic M1 receptor allosteric agonist. It activates M1 through an allosteric site rather than the orthosteric acetylcholine binding site, which is likely critical for its selectivity. Muscarinic 1 (M1) receptors are expressed in brain regions responsible for attention and memory, including hippocampus, cortex, and striatum. M1 activation is a proposed mechanism for increasing information processing in disease states, such as Alzheimerμs. M1 agonists are being studied as potential therapeutic agents to tre at Alzheimer′s disease and the cognitive and negative symptoms of schizophrenia.
TBPB Preparation Products And Raw materials
Raw materials
Preparation Products
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TBPB Suppliers
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2922
- Advantage
- 55
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7552
- Advantage
- 61
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4861
- Advantage
- 58
- Tel
- +86-21-5821 5861
- Fax
- +86-21-5106 2861
- sales@letopharm.com
- Country
- China
- ProdList
- 2384
- Advantage
- 58
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4573
- Advantage
- 55
- Tel
- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
- Country
- China
- ProdList
- 1005
- Advantage
- 55
- Tel
- +86-21-58447131
- Fax
- +86-21-61642470
- 1724405207@qq.com
- Country
- China
- ProdList
- 472
- Advantage
- 55
- Tel
- 15261860116
- Fax
- 86-025-84106591
- sales@elsa-biotech.com
- Country
- China
- ProdList
- 99
- Advantage
- 55
- Tel
- 021-50908862，442785678，326799392 18721037013
- Fax
- 021-50908862
- siyansales@126.com
- Country
- China
- ProdList
- 9627
- Advantage
- 58
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View Lastest Price from TBPB manufacturers
Career Henan Chemica Co
- Product
- TBPB 634616-95-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- MIn98%HPLC/LC
- Supply Ability
- 100KGS
- Release date
- 2020-10-29