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SAM-315

Product Name
SAM-315
CAS No.
744218-85-7
Chemical Name
SAM-315
Synonyms
SAM-315;WAY-255315;3-naphthalen-1-ylsulfonyl-5-piperazin-1-yl-2H-indazole;1H-Indazole, 3-(1-naphthalenylsulfonyl)-5-(1-piperazinyl)-
CBNumber
CB52628526
Molecular Formula
C21H20N4O2S
Formula Weight
392.47
MOL File
744218-85-7.mol
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SAM-315 Property

Boiling point:
709.1±50.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
pka
11.05±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0014190
Product name
WAY-255315
Purity
95.00%
Packaging
5MG
Price
$501.42
Updated
2021/12/16
Chemenu
Product number
CM334116
Product name
3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole
Purity
95%+
Packaging
1g
Price
$979
Updated
2021/12/16
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SAM-315 Chemical Properties,Usage,Production

Uses

SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6, with Ki and IC50 of 1.1 nM and 4.6 nM, respectively. SAM-315 significantly increases acetylcholine and glutamate release in hippocampus of the brain[1].

IC 50

5-HT6 Receptor: 4.6 nM (IC50)

References

[1] 5-Piperazinyl-3-sulfonylindazoles as Potent and Selective 5-Hydroxytryptamine-6 Antagonists J. Med. Chem., Article ASAP DOI: 10.1021/jm1007825 Publication Date (Web): October 8, 2010
[2] Kevin G Liu, et al. 5-Piperazinyl-3-sulfonylindazoles as Potent and Selective 5-Hydroxytryptamine-6 Antagonists. J Med Chem. 2010 Nov 11;53(21):7639-46. DOI:10.1021/jm1007825

SAM-315 Preparation Products And Raw materials

Raw materials

Preparation Products

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SAM-315 Suppliers

China 11 Global 11
Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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Beijing Yisiyan Technology Research Center
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010-56645598 13366904824
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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Nanjing KaiMubo Pharmaceutical Co., Ltd.
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025-66162170
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025-66162170
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China
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Chemleader Biomedical Co., Limited.
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sales@MedChemLeader.com
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Chunchuang (Wuhan) Technology Co., Ltd
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15727060112
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Abmole Bioscience Inc.
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sales@abmole.cn
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China
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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-025-66113011 18626450290
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China
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Olix (Shanghai) Pharmaceutical Technology Co., Ltd
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17316404525 17316404525
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744218-85-7, SAM-315Related Search:

WAY-600 MAY-262611 N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol

  • SAM-315
  • WAY-255315
  • 3-naphthalen-1-ylsulfonyl-5-piperazin-1-yl-2H-indazole
  • 1H-Indazole, 3-(1-naphthalenylsulfonyl)-5-(1-piperazinyl)-
  • 744218-85-7