ChemicalBook > CAS DataBase List > (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)

Product Name
(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)
CAS No.
330785-81-4
Chemical Name
(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)
Synonyms
Avanafil Intermediate II;ethyl 4-(3-chloro-4-MethoxybenzylaMino)-2-(Methylthio)pyriMidine-5-carboxylate;4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester;AvafilImpurity43;RSYY（Lifitegrast)-1;INTERMEDIATE OF AVANAFIL;Avanafil Intermediate Impurity;330785-81-4;5-Pyrimidinecarboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)me...;4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine
CBNumber
CB52638736
Molecular Formula
C16H18ClN3O3S
Formula Weight
367.85
MOL File
330785-81-4.mol
More
Less

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Property

Boiling point:
514.9±45.0 °C(Predicted)
Density 
1.33±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
2.70±0.10(Predicted)
form 
powder
color 
White
More
Less

Safety

HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
C367865
Product name
4-(3-Chloro-4-methoxybenzylamino)-5-ethoxycarbonyl-2-methylthiopyrimidine
Packaging
25g
Price
$910
Updated
2021/12/16
AK Scientific
Product number
3646AH
Product name
Ethyl4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Packaging
1g
Price
$295
Updated
2021/12/16
Apolloscientific
Product number
OR48263
Product name
Ethyl4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylthio)pyrimidine-5-carboxylate
Packaging
1g
Price
$27
Updated
2021/12/16
SynQuest Laboratories
Product number
8H65-5-X0
Product name
Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylthio)pyrimidine-5-carboxylate
Packaging
1g
Price
$29
Updated
2021/12/16
Apolloscientific
Product number
OR48263
Product name
Ethyl4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylthio)pyrimidine-5-carboxylate
Packaging
5g
Price
$47
Updated
2021/12/16
More
Less

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Chemical Properties,Usage,Production

Uses

4-(3-Chloro-4-methoxybenzylamino)-5-ethoxycarbonyl-2-methylthiopyrimidine is an intermediate for Avanafil (A794670) derivatives. Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) Suppliers

China 170 France 1 India 3 United Kingdom 1 United States 1 Global 176
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
More
Less

View Lastest Price from (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester) manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester 330785-81-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-12-05
Shanghai Joiny Pharmaceutical Co.,LTD
Product
4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester 330785-81-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2023-08-31
PNP Biotech Co. Ltd
Product
5-Pyrimidinecarboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-, ethyl ester 330785-81-4
Price
US $0.00/KG
Min. Order
25KG
Purity
98%-99%
Supply Ability
Inquiry
Release date
2022-10-21

330785-81-4, (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)Related Search:

3-Chloroperoxybenzoic acid INTERMEDIATES Dry shellfish Acetylene Iodixanol

  • (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)
  • 4-(3-Chloro-4-Methoxy-benzylaMino)-2-Methylsulfanyl-pyriMidine-5-carboxylic acid ethyl ester
  • 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
  • 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine
  • ethyl 4-(3-chloro-4-MethoxybenzylaMino)-2-(Methylthio)pyriMidine-5-carboxylate
  • Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulphanyl)pyrimidine-5-carboxylate, 4-[(3-Chloro-4-methoxybenzyl)amino]-5-(ethoxycarbonyl)-2-(methylthio)pyrimidine
  • Avanafil Intermediate II
  • (5-PyriMidinecarboxylicacid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-(Methylthio)-,ethyl ester)###NA
  • ethyl 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate
  • INTERMEDIATE OF AVANAFIL
  • Avanafil intermediates，5-Pyrimidinecarboxylicacid, 4-[[(3- chloro-4- methoxyphenyl)methyl]amino]-2- (methylthio)-, ethyl ester
  • 5-Pyrimidinecarboxylicacid, 4-[[(3-chloro-4-methoxyphenyl)me...
  • "5-Pyrimidinecarboxylic acid,4-[[(3-chloro-4-methoxyphenyl) methyl]amino]-2-(methylthio)ethyl este"
  • AvafilImpurity43
  • Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate
  • Avanafil Intermediate Impurity
  • RSYY（Lifitegrast)-1
  • Ethyl 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylate
  • <font color="#ff0000">330785-81-4</font>
  • 4- (3-Chloro-4-methoxyphenylamino) -5-ethoxycarbonyl-2-methylthiapyrimidine
  • 330785-81-4
  • 330785-84-4
  • 330785-81-4