J 147

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Product Name: J 147
CAS No.: 1146963-51-0
Chemical Name: J 147
Synonyms: J 147;CS-1446;J147-API;J147/J-147;J-147?, >98%;Nootropic J147;J 147(Nootropic Powder);CAS 1146963-51-0 J 147;n-(2,4-dimethylphenyl)-n-(3-methoxybenzylidene)acetohydrazide;N-(2,4-DIMETHYLPHENYL)-N'-(3-METHOXYBENZYLIDENE)ACETOHYDRAZIDE
CBNumber: CB52652639
Molecular Formula: C18H17F3N2O2
Formula Weight: 350.33
MOL File: 1146963-51-0.mol

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J 147 Property

Boiling point:: 412.8±55.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO:68.0(Max Conc. mg/mL);194.1(Max Conc. mM)
form: Powder
pka: 0.80±0.50(Predicted)
color: Off-white to pink
InChI: InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3
InChIKey: HYMZAYGFKNNHDN-UHFFFAOYSA-N
SMILES: C(N(C1=CC=C(C)C=C1C)N=CC1=CC=CC(OC)=C1)(=O)C(F)(F)F

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 5081
Product name: J147
Purity: ≥99%(HPLC)
Packaging: 10
Price: $182
Updated: 2021/12/16

Tocris

Product number: 5081
Product name: J147
Purity: ≥99%(HPLC)
Packaging: 50
Price: $745
Updated: 2021/12/16

TRC

Product number: J210300
Product name: J147
Packaging: 10mg
Price: $165
Updated: 2021/12/16

ApexBio Technology

Product number: B5804
Product name: J147
Packaging: 10mg
Price: $171
Updated: 2021/12/16

ChemScene

Product number: CS-3688
Product name: J-147
Purity: 99.87%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

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J 147 Chemical Properties,Usage,Production

Uses

J 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer''s disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer''s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.

Definition

ChEBI: J147 is an anilide.

benefits

J 147 improves heart health by lowering blood pressure, boosts metabolism, supports digestive and immune system function, improves cognitive function, has no side effects, and increases physical strength with long-term use. Once there is significant weight loss after taking it, this supplement helps people maintain their weight by reducing cravings and increasing energy levels. Since it helps suppress the hunger hormone that causes overeating, people who use J147 capsules for a long time are more likely to maintain their weight

Biological Activity

J 147 is a potent neuroprotective and neurotrophic compound. Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. Enhances memory in wild type rats. Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively. Orally active.

storage

Store at +4°C

J 147 Preparation Products And Raw materials

Raw materials

Preparation Products

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J 147 Suppliers

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View Lastest Price from J 147 manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: J-147 1146963-51-0
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-29

Sinoway Industrial co., ltd.

Product: J 147 1146963-51-0
Price: US $0.00-0.00/G/Bag
Min. Order: 100G/Bag
Purity: 99% up, High Density
Supply Ability: 100 KG
Release date: 2024-06-27

HangZhou RunYan Pharma Technology Co.,LTD.

Product: J-147 1146963-51-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.0%min. HPLC
Supply Ability: 10000
Release date: 2024-09-22

1146963-51-0, J 147Related Search:

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N-(2,4-DIMETHYLPHENYL)-N'-(3-METHOXYBENZYLIDENE)ACETOHYDRAZIDE

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CS-1446

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J 147(Nootropic Powder)

N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide

CAS 1146963-51-0 J 147

oxidase,dopamine,brain,disease,MAO B,Inhibitor,SLC6A3,DAT,J 147,blood,neuroprotective,inhibit,Monoamine Oxidase,MAO,transporte,monoamine,Dopamine Transporter,Alzheimer,BBB,barrier,J-147

N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide

n-(2,4-dimethylphenyl)-n-(3-methoxybenzylidene)acetohydrazide

N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide

1146963-51-0

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Pharmaceuticals

1146963-51-0