(+/-)-THIOPENTAL

Product Name: (+/-)-THIOPENTAL
CAS No.: 76-75-5
Chemical Name: (+/-)-THIOPENTAL
Synonyms: Intraval;Nesdonal;Thiothal;Pentothal;Tiopentale;THIOPENTAL;Thiomebumal;THIOPENTONE;PENTOTHAL ACID;Thiopental CRS
CBNumber: CB5265910
Molecular Formula: C11H18N2O2S
Formula Weight: 242.34
MOL File: 76-75-5.mol

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(+/-)-THIOPENTAL Property

Melting point:: 158-160°C
Density: 1.1789 (rough estimate)
refractive index: 1.5440 (estimate)
Flash point:: 11℃
storage temp.: 2-8°C
solubility: ethanol: complete50mg/mL
pka: 7.11±0.40(Predicted)
form: Solid
color: White to Off-White
Water Solubility: 50mg/L(25 ºC)
CAS DataBase Reference: 76-75-5(CAS DataBase Reference)
EPA Substance Registry System: 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (76-75-5)

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Safety

Hazard Codes: Xn,T,F
Risk Statements: 22-39/23/24/25-23/24/25-11
Safety Statements: 36/37/39-45-36/37-16-7
RIDADR: UN 1230 3/PG 2
WGK Germany: 3
RTECS: CQ6300000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2933595960
Hazardous Substances Data: 76-75-5(Hazardous Substances Data)
Toxicity: cyt-hmn:leu 1500 mg/L TGANAK18(1),13,84

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T1019
Product name: (±)-Thiopental
Packaging: 10mg
Price: $76.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1661002
Product name: Thiopental
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 250mg
Price: $544
Updated: 2024/03/01

Sigma-Aldrich

Product number: T1022
Product name: (±)Thiopental solution
Purity: 1.0mg/mL in methanol, analytical standard, for drug analysis
Packaging: 1ml
Price: $160
Updated: 2024/03/01

Usbiological

Product number: 290137
Product name: Thiopental
Packaging: 100mg
Price: $370
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004399
Product name: THIOPENTAL
Purity: 95.00%
Packaging: 250MG
Price: $704.55
Updated: 2021/12/16

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(+/-)-THIOPENTAL Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Originator

Pentothal,Abbott

Uses

A thio-derivative of Barbituric acid. Controlled substance (depressant). Anesthetic

Definition

ChEBI: Thiopental is a barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and sec-pentyl groups. It has a role as an anticonvulsant, a sedative, an environmental contaminant, a xenobiotic, a drug allergen and an intravenous anaesthetic. It is functionally related to a 2-thiobarbituric acid. It is a conjugate acid of a thiopental(1-).

Manufacturing Process

130 g of ethyl (1-methylbutyl) malonic ester is added to a concentrated solution of sodium ethylate prepared from 34 g of sodium in absolute alcohol; with stirring, 60 g of finely divided thiourea is added, and, the mixture refluxed for 10 hours. Most or all of the solvent is evaporated and the residual mass is dissolved in cold water. The barbituric acid derivative so formed is precipitated by the addition of dilute hydrochloric acid. It may be 1 purified by solution in dilute ammonium hydroxide solution and precipitated by carbon dioxide, followed by recrystallization from 95% alcohol. The ethyl (1- methylbutyl)thiobarbituric acid so obtained is a white crystalline solid, melting at 158-159°C and readily forming salts with alkalies.

brand name

Thiopental is BAN.

Therapeutic Function

Narcotic analgesic, Anesthetic

Safety Profile

Poison by intraperitoneal, intravenous, and rectal routes. Moderately toxic by ingestion. An experimental teratogen. Human mutation data reported. A short-acting intravenous anesthetic. When heated to decomposition it emits very toxic fumes of NOx and SOx

(+/-)-THIOPENTAL Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-THIOPENTAL Suppliers

Canada 1 China 19 France 1 Germany 1 India 5 Switzerland 1 United Kingdom 5 United States 11 Global 44

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9503
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9506
Advantage: 60

Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-87576359 17691182729
Fax: 029-88380327
Email: 1018@dideu.com
Country: China
ProdList: 1982
Advantage: 58

Xi'an MC Biotech, Co., Ltd.

Tel: 029-89275612 +8618991951683
Fax: 8618991951683
Email: mcbio_sales@163.com
Country: China
ProdList: 2255
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
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Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23931
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 15093356674;
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29826
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
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Email: sean.lv@synzest.com
Country: China
ProdList: 10787
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 9946
Advantage: 58

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View Lastest Price from (+/-)-THIOPENTAL manufacturers

Career Henan Chemical Co

Product: (+/-)-THIOPENTAL 76-75-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%HPLC
Supply Ability: 100KG
Release date: 2020-02-05

76-75-5, (+/-)-THIOPENTALRelated Search:

thialbarbital Thiotetramalum Methitural Barbituric acid Thiopental Sodium THIOPENTAL ACID THIOPENTAL, [2-14C] 5-ALLYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID (+/-)-THIOPENTAL R-(+)-Thiopental sodium S-(-)-Thiopental sodium thialbarbital sodium S-Thiopental,S-(-)-Thiopental (R)-(+)-Thiopental,(R)-Thiopental Thiopental-d5 S(-)-Thioamylal sodium R(+)-Thioamylal sodium

5-ETHYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID

5-ETHYL-5-PENTAN-2-YL-2-SULFANYL-1H-PYRIMIDINE-4,6-DIONE

5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione

(±)thiopental solution

2-Thio-5-ethyl-5-sec-pentylbarbituric acid

4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI)

Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio- (8CI)

PENTOTHAL ACID

5-Ethyl-5-(1-methylbutyl)-2-thiobarbitirobic acid

(+-)-thiopental methanol solution

(+,-)-thiopental free acid--dea*schedule iii item

5-Ethyl-5-[(S)-1-methylbutyl]-2-thioxo-1,2-dihydropyrimidine-4,6(3H,5H)-dione

Thiopental CIII (250 mg)

Thiopental for system suitability

Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-

Intraval

Nesdonal

Penthiobarbital

Pentothal

Pentothiobarbital

Thiomebumal

Thiopentobarbital

Thiopentobarbitone

Thiopentobarbituric acid

Thiothal

Tiopentale

THIOPENTONE

(+/-)-THIOPENTAL

THIOPENTAL

(1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-6

4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-

5-ethyl-5-(1-methylbutyl)-2-thio-barbituricaci

5-Ethyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione

5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione

Thiopental CRS

Thiopental for system suitability CRS

('+/-)-THIOPENTAL

Thiopental for system suitability (Y0001478)

76-75-5

C11H18N2O2S

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