BroMosporine

ChemicalBook > CAS DataBase List > BroMosporine

Product Name: BroMosporine
CAS No.: 1619994-69-2
Chemical Name: BroMosporine
Synonyms: CS-921;BroMosporine;BroMosporine USP/EP/BP;KASUMI-1,HIV,AIDS,Human immunodeficiency virus,MV4;N-[6-(3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate;ethyl 3-Methyl-6-(4-Methyl-3-(MethylsulfonaMido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-ylcarbaMate;Carbamic acid, N-[3-methyl-6-[4-methyl-3-[(methylsulfonyl)amino]phenyl]-1,2,4-triazolo[4,3-b]pyridazin-8-yl]-, ethyl ester;11,Bromosporine,inhibit,AML,colorectal cancer,CDK,antitumor,T cells,HCT116,Apoptosis,HT29,anticancer,Epigenetic Reader Domain,Inhibitor,Cyclin dependent kinase
CBNumber: CB52676961
Molecular Formula: C17H20N6O4S
Formula Weight: 404.44
MOL File: 1619994-69-2.mol

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BroMosporine Property

Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in DMSO (up to 25 mg/ml)
pka: 6.21±0.46(Predicted)
form: solid
color: Off-white
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14119
Product name: Bromosporine
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 14119
Product name: Bromosporine
Purity: ≥98%
Packaging: 5mg
Price: $108
Updated: 2024/03/01

Cayman Chemical

Product number: 14119
Product name: Bromosporine
Purity: ≥98%
Packaging: 10mg
Price: $195
Updated: 2024/03/01

Cayman Chemical

Product number: 14119
Product name: Bromosporine
Purity: ≥98%
Packaging: 25mg
Price: $353
Updated: 2024/03/01

Tocris

Product number: 4758
Product name: Bromosporine
Purity: ≥98%(HPLC)
Packaging: 10
Price: $287
Updated: 2021/12/16

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BroMosporine Chemical Properties,Usage,Production

Description

Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1?Bromosporine was able to reactivate HIV-1 replication in different latency models.2

Uses

Bromosporine is a broad spectrum inhibitor for bromodomains.

target

bromodomain

storage

Store at +4°C

References

1) Picaud?et al.?(2016),?Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci. Adv.?2?e1600760 2) Pan?et al.?(2017),?The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget?8?94104

BroMosporine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BroMosporine manufacturers

Career Henan Chemical Co

Product: BroMosporine 1619994-69-2
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

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BroMosporine

ethyl 3-Methyl-6-(4-Methyl-3-(MethylsulfonaMido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-ylcarbaMate

N-[6-(3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate

CS-921

Carbamic acid, N-[3-methyl-6-[4-methyl-3-[(methylsulfonyl)amino]phenyl]-1,2,4-triazolo[4,3-b]pyridazin-8-yl]-, ethyl ester

BroMosporine USP/EP/BP

11,Bromosporine,inhibit,AML,colorectal cancer,CDK,antitumor,T cells,HCT116,Apoptosis,HT29,anticancer,Epigenetic Reader Domain,Inhibitor,Cyclin dependent kinase

KASUMI-1,HIV,AIDS,Human immunodeficiency virus,MV4

1619994-69-2

Inhibitors

API