tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate

Product Name: tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate
CAS No.: 558442-96-9
Chemical Name: tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate
Synonyms: 105471;tert-butyl N-(4-morpholinocyclohexyl)carbamate;tert-Butyl (trans-4-morpholinocyclohexyl)carbamate;tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate;Carbamic acid, N-[trans-4-(4-morpholinyl)cyclohexyl]-, 1,1-dimethylethyl ester
CBNumber: CB52684445
Molecular Formula: C15H28N2O3
Formula Weight: 284.39
MOL File: 558442-96-9.mol

More

Less

tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Property

Boiling point:: 396.3±37.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 12.50±0.40(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 120887
Product name: tert-Butyl((1r,4r)-4-morpholinocyclohexyl)-carbamate
Purity: 97%
Packaging: 5g
Price: $1486
Updated: 2021/12/16

Matrix Scientific

Product number: 120887
Product name: tert-Butyl((1r,4r)-4-morpholinocyclohexyl)-carbamate
Purity: 97%
Packaging: 10g
Price: $2376
Updated: 2021/12/16

Ambeed

Product number: A123528
Product name: tert-Butyl(trans-4-morpholinocyclohexyl)carbamate
Purity: 95+%
Packaging: 100mg
Price: $89
Updated: 2021/12/16

Ambeed

Product number: A123528
Product name: tert-Butyl(trans-4-morpholinocyclohexyl)carbamate
Purity: 95+%
Packaging: 250mg
Price: $111
Updated: 2021/12/16

Crysdot

Product number: CD11104477
Product name: tert-Butyl(trans-4-morpholinocyclohexyl)carbamate
Purity: 95+%
Packaging: 1g
Price: $294
Updated: 2021/12/16

More

Less

tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Chemical Properties,Usage,Production

Synthesis

5414-19-7

177906-48-8

558442-96-9

The general procedure for the synthesis of tert-butyl (trans-4-morpholinocyclohexyl)carbamate from 2,2'-dibromodiethyl ether and tert-butyl trans-(4-aminocyclohexyl)carbamate was as follows: 21.43 g (0.1 mol) of tert-butyl N-(trans-4-aminocyclohexyl)carbamate was dissolved into 250 mL of N,N-dimethylformamide, followed by addition of 16.76 mL (0.12 mol) bis(2-bromoethyl) ether and 34.85 mL (0.25 mol) triethylamine. The reaction mixture was stirred at 70°C for 6 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate, and the organic layer was washed sequentially with aqueous sodium carbonate and saturated brine solution, and then dried over anhydrous sodium sulfate. The solvent was again removed by reduced pressure distillation and the residue was purified by silica gel column chromatography (elution gradient: from pure chloroform to chloroform/methanol=30/1) to give 19.92 g (70% yield) of tert-butyl (trans-4-morpholino cyclohexyl)carbamate.

References

[1] Patent: EP1775298, 2007, A1. Location in patent: Page/Page column 33-34

tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate Suppliers

China 25 India 2 United States 2 Global 29

ChemShuttle, Inc.

Tel: 0510-83588313-811 18800520310
Email: sales@chemshuttle.com
Country: China
ProdList: 2999
Advantage: 62

Shanghai Raise Chemical Technology Co.,Ltd

Tel: 15026594951
Fax: 0556-5030632
Email: rs@raise-chem.com
Country: China
ProdList: 4454
Advantage: 55

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai Uchem Inc.

Tel: 15618758386; 15618758386
Fax: QQ:3004479444
Email: sales3@myuchem.com
Country: China
ProdList: 1988
Advantage: 55

ShangHai Wisacheam Pharmaceutical Co., Ltd.

Tel: 13817485796
Fax: QQ:895624079
Email: tim@wisacheampharm.com
Country: China
ProdList: 3593
Advantage: 58

Wuxi KaideRui Pharmaceutical Technology Co., Ltd

Tel: 19906241957
Fax: -
Email: 1557216087@qq.com
Country: China
ProdList: 1837
Advantage: 55

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22345
Advantage: 58

Wuxi jinluoli Pharmaceutical Technology Co., Ltd.

Tel: 18021193238
Fax: QQ：534936027
Email: 534936027@qq.com
Country: China
ProdList: 363
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Shanghai Pleikon Chemical Technology Co., Ltd

Tel: 021-021-54321516 17717324060
Email: 2719672468@qq.com
Country: China
ProdList: 2032
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1169
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 15811073878
Email: 2559355526@qq.com
Country: China
ProdList: 10701
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054;
Email: trendseenbio@gmail.com
Country: China
ProdList: 9069
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: sales@pharmablock.com
Country: China
ProdList: 7268
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

Suzhou ARTK Medchem Co., Ltd.

Tel: +86-512-68323658 +86-18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 39002
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 11681
Advantage: 58

558442-96-9, tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMateRelated Search:

TERT-BUTYL (6-BROMO-3-METHYLPYRIDIN-2-YL)CARBAMATE (6-Oxo-1,6-dihydro-pyridin-3-yl)-carbaMic acid tert-butyl ester Carbamic acid, N-[(1R)-1-cyano-2-(1,1-dimethylethoxy)ethyl]-, 1,1-dimethylethyl ester tert-Butyl (((tert-butoxycarbonyl)imino)(3,5-dimethyl-4-oxo-1,3,5-triazinan-1-yl)methyl)carbam TERT-BUTYL 6-IODOHEXYLCARBAMATE N-(BOC-AMINO)PHTHALIMIDE tert-butyl 1-(2-hydroxypropyl)piperidin-4-ylcarbaMate tert-butyl (4-fluoro-4-phenylcyclohexyl)carbamate Carbamic acid, (4-ethynylphenyl)-, 1,1-dimethylethyl ester (9CI) (R)-tert-butyl (1-(1H-indol-3-yl)propan-2-yl)carbamate

tert-butyl ((1r,4r)-4-Morpholinocyclohexyl)carbaMate

tert-Butyl (trans-4-morpholinocyclohexyl)carbamate

105471

Carbamic acid, N-[trans-4-(4-morpholinyl)cyclohexyl]-, 1,1-dimethylethyl ester

tert-butyl N-(4-morpholinocyclohexyl)carbamate

558442-96-9