Kif15-IN-2

Product Name: Kif15-IN-2
CAS No.: 672926-33-9
Chemical Name: Kif15-IN-2
Synonyms: Kif15-IN-2;Kif15 inhibitor 2;Kif15IN2,Kif-15-IN-2,Kif15 IN 2;3(2H)-Quinazolineacetamide, 1,4-dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-, (αS)-;(alphaS)-1,4-Dihydro-alpha-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide
CBNumber: CB52685927
Molecular Formula: C20H20N6O4S
Formula Weight: 440.48
MOL File: 672926-33-9.mol

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Kif15-IN-2 Property

Density: 1.409±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: solid
pka: 7.58±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-2698
Product name: Kif15-IN-2
Purity: 98.64%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

ApexBio Technology

Product number: B3281
Product name: Kif15-IN-2
Packaging: 5mg
Price: $513
Updated: 2021/12/16

ChemScene

Product number: CS-2698
Product name: Kif15-IN-2
Purity: 98.64%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-2698
Product name: Kif15-IN-2
Purity: 98.64%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

ChemScene

Product number: CS-2698
Product name: Kif15-IN-2
Purity: 98.64%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

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Kif15-IN-2 Chemical Properties,Usage,Production

Biological Activity

kif15-in-2, a potent kif15 kinesin inhibitor; inhibits cellular proliferation in various tumor cell lines [1].kif15,also known as kinesin-12 and hklp2, is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth [2]. kif15 is a kinesin-related protein whose mitotic homologues are believed to crosslink and immobilize spindle microtubules.kif15 is involved in maintainingbipolar microtubulespindle apparatusin dividing cells and shares redundant functions withkif11 [3].

References

[1]. preparation of quinazolinediones as kif15 kinesin inhibitors for treating cellular proliferative disorders. pat. appl. publ. (2004), us 20040053948 a1 20040318.
[2]. buster d w, baird d h, yu w, et al. expression of the mitotic kinesin kif15 in postmitotic neurons: implications for neuronal migration and development[j]. journal of neurocytology, 2003, 32(1): 79-96.
[3]. vanneste d, takagi m, imamoto n, et al. the role of hklp2 in the stabilization and maintenance of spindle bipolarity[j]. current biology, 2009, 19(20): 1712-1717.

Kif15-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Kif15-IN-2 Suppliers

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672926-33-9, Kif15-IN-2Related Search:

2-Methyl-4-isothiazolin-3-one

Kif15-IN-2

(alphaS)-1,4-Dihydro-alpha-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide

Kif15 inhibitor 2

3(2H)-Quinazolineacetamide, 1,4-dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-, (αS)-

Kif15IN2,Kif-15-IN-2,Kif15 IN 2

672926-33-9

C20H20N6O4S