BOC-GLU(OBZL)-OME

Product Name: BOC-GLU(OBZL)-OME
CAS No.: 59279-58-2
Chemical Name: BOC-GLU(OBZL)-OME
Synonyms: BOC-GLU(OBZL)-OME;Boc-L-Glu(OBzl)-OMe;(Tert-Butoxy)Carbonyl Glu(OBzl)-OMe;Boc-L-glutamicacid-benzyla-methylester;Boc-L-Glutamic Acid 5-Benzyl 1-Methyl Ester;Boc-L-glutamic acid γ-benzyl α-methyl ester;BOC-L-GLUTAMIC ACID-Y-BENZYL A-METHYL-DIESTER;5-Benzyl 1-Methyl (S)-2-(Boc-amino)pentanedioate;BOC-L-GLUTAMIC ACID-GAMMA-BENZYL ALPHA-METHYL-DIESTER;BOC-L-GLUTAMIC ACID .GAMMA.-BENZYL .ALPHA.-METHYL ESTER
CBNumber: CB5269761
Molecular Formula: C18H25NO6
Formula Weight: 351.39
MOL File: 59279-58-2.mol

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BOC-GLU(OBZL)-OME Property

Melting point:: 38-41 °C
Boiling point:: 471.2±40.0 °C(Predicted)
Density: 1.144±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 10.96±0.46(Predicted)
Appearance: White to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS112951
Product name: Boc-Glu(Obzl)-OMe
Purity: 95%
Packaging: 5G
Price: $149
Updated: 2021/12/16

AK Scientific

Product number: 8817AB
Product name: Boc-Glu(OBzl)-OMe
Packaging: 5g
Price: $182
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0009071
Product name: (S)-5-BENZYL 1-METHYL-2-(TERT-BUTOXYCARBONYLAMINO)PENTANEDIOATE
Purity: 95.00%
Packaging: 5MG
Price: $505.26
Updated: 2021/12/16

Activate Scientific

Product number: AS112951
Product name: Boc-Glu(Obzl)-OMe
Purity: 95%
Packaging: 25g
Price: $583
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0009071
Product name: (S)-5-BENZYL 1-METHYL-2-(TERT-BUTOXYCARBONYLAMINO)PENTANEDIOATE
Purity: 95.00%
Packaging: 5G
Price: $735
Updated: 2021/12/16

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BOC-GLU(OBZL)-OME Chemical Properties,Usage,Production

Synthesis

13574-13-5

74-88-4

59279-58-2

Step 1: Iodomethane (1.01 mL, 16.3 mmol) was slowly added dropwise to a mixed solution of THF (14.82 mmol) and DMF (25 mL) of (2S)-5-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}-5-oxopentanoic acid (5.00 g) along with K2CO3 (2.25 g, 16.3 mmol). The reaction mixture was stirred at room temperature for about 3 hours before iodomethane (1.01 mL, 16.3 mmol) was added again. Subsequently, EtOAc was added to the reaction mixture and washed three times with 10% Na2S2O3 solution and then dried with MgSO4. After concentration under reduced pressure to remove the solvent, the crude product was purified by silica gel column chromatography (100:1, followed by 50:1 CHCl3/MeOH) to afford methyl (S)-5-benzyl-2-((tert-butoxycarbonyl)amino)pentanedioate (4.20 g, 12.23 mmol, 82% yield). m/z of C18H25NO6 was detected by ESIMS as 352 (M + H ).

References

[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 5, p. 1899 - 1913
[2] Patent: US2008/318957, 2008, A1. Location in patent: Page/Page column 41-42
[3] Patent: WO2012/109164, 2012, A1. Location in patent: Page/Page column 39
[4] Organic and Biomolecular Chemistry, 2007, vol. 5, # 12, p. 1915 - 1923
[5] Organic Letters, 2016, vol. 18, # 9, p. 1968 - 1971

BOC-GLU(OBZL)-OME Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-GLU(OBZL)-OME Suppliers

China 49 Germany 2 India 1 Japan 1 Switzerland 1 United States 6 Global 60

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Shanghai YuanYe Biotechnology Co., Ltd.

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View Lastest Price from BOC-GLU(OBZL)-OME manufacturers

Career Henan Chemical Co

Product: BOC-GLU(OBZL)-OME 59279-58-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-18

59279-58-2, BOC-GLU(OBZL)-OMERelated Search:

L-Glutamic acid Boc-L-Glutamic acid BOC-L-GLUTAMIC ACID DIBENZYL ESTER 4-[T-BUTYLOXYCARBONYL-(GAMMA-BENZYL)-GLUTAMYLOXYMETHYL]-PHENYLACETIC ACID BOC-GLU(OBZL)-ONP Boc-L-glutamic acid γ-benzyl ester N-carboxyanhydride BOC-GLU(OBZL)-OME

BOC-GLU(OBZL)-OME

BOC-L-GLUTAMIC ACID GAMMA-BENZYL ESTER ALPHA-METHYL ESTER

BOC-L-GLUTAMIC ACID-GAMMA-BENZYL ALPHA-METHYL-DIESTER

Boc-L-Glutamic Acid 5-Benzyl 1-Methyl Ester

Boc-L-Glu(OBzl)-OMe

N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID GAMMA-BENZYL ESTER ALPHA-METHYL ESTER

Boc-L-glutamic acid γ-benzyl α-methyl ester

Boc-L-glutamicacid-benzyla-methylester

BOC-L-GLUTAMIC ACID-Y-BENZYL A-METHYL-DIESTER

BOC-L-GLUTAMIC ACID .GAMMA.-BENZYL .ALPHA.-METHYL ESTER

(S)-5-benzyl 1-methyl 2-(tert-butoxycarbonylamino)pentanedioate

Boc-Glu(OBzl)-OMe Boc-L-glutaMic acid γ-benzyl α-Methyl ester

(Tert-Butoxy)Carbonyl Glu(OBzl)-OMe

5-benzyl 1-methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}pentanedioate

L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-methyl 5-(phenylmethyl) ester

N-α-(t-Butoxycarbonyl)-L-glutamic acid γ-benzyl ester α-methyl ester

5-Benzyl 1-Methyl (S)-2-(Boc-amino)pentanedioate

(S)-Methyl 5-benzyl-2-((tert-butoxycarbonyl)amino)glutarate

59279-58-2

C18H25NO6