2-Methyl-1,3-cyclopentanedione

Product Name: 2-Methyl-1,3-cyclopentanedione
CAS No.: 765-69-5
Chemical Name: 2-Methyl-1,3-cyclopentanedione
Synonyms: 1,3-Cyclopentanedione, 2-methyl-;2-Methylcyclopentane-1,3-dione;2-Methyl-1,3-cyclopentadione;-1,3-cycL;2-Methyl-1;METHYLCYCLE-D;2-Methylcyclopentan-1,3-dion;2-METHYLCYCLOPENTAN-1,3-DIONE;2-Methyl-1,3-dioxocyclopentane;2-METHYL-1,3-CYCLOPENTANEDIONE
CBNumber: CB5272422
Molecular Formula: C6H8O2
Formula Weight: 112.13
MOL File: 765-69-5.mol

More

Less

2-Methyl-1,3-cyclopentanedione Property

Melting point:: 212-215 °C (lit.)
Boiling point:: 213°C (estimate)
Density: 1.0795 (rough estimate)
refractive index: 1.4550 (estimate)
storage temp.: Store below +30°C.
solubility: Solubility in hot Methanol (almost transparency).
pka: 10.83±0.20(Predicted)
form: Crystalline Powder
color: Light beige to tan
PH: 2.95 at 24.7℃ and 10g/L
BRN: 1237255
InChIKey: HXZILEQYFQYQCE-UHFFFAOYSA-N
LogP: -0.8 at 30℃ and pH7.66
CAS DataBase Reference: 765-69-5(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Cyclopentanedione, 2-methyl-(765-69-5)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29142900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 117021
Product name: 2-Methyl-1,3-cyclopentanedione
Purity: 99%
Packaging: 5g
Price: $25.46
Updated: 2025/07/31

Sigma-Aldrich

Product number: 117021
Product name: 2-Methyl-1,3-cyclopentanedione
Purity: 99%
Packaging: 25g
Price: $54.81
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.10504
Product name: 2-Methyl-1,3-cyclopentanedione
Purity: for synthesis
Packaging: 10g
Price: $64.1
Updated: 2022/05/15

TCI Chemical

Product number: M0901
Product name: 2-Methyl-1,3-cyclopentanedione
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: M0901
Product name: 2-Methyl-1,3-cyclopentanedione
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $113
Updated: 2025/07/31

More

Less

2-Methyl-1,3-cyclopentanedione Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE TO TAN CRYSTALLINE POWDER

Uses

2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

Uses

2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization.

Synthesis Reference(s)

Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676

Synthesis

614-45-9

3859-41-4

765-69-5

The general procedure for the synthesis of 2-methyl-1,3-cyclopentanedione from 1,3-cyclopentanedione and tert-butyl peroxybenzoate was as follows: 1,3-cyclopentanedione (0.098 g, 1 mmol), tert-butyl peroxybenzoate (0.58 g, 3 mmol), CuCl (0.01 g, 0.1 mmol), and 2 mL of acetic acid were added to a reaction flask, and the reaction was carried out at 120 °C Reaction at 120°C. The progress of the reaction was monitored by thin layer chromatography (TLC) until the reaction was complete. After completion of the reaction, the crude product was purified by column chromatography (eluent ratio of petroleum ether:ethyl acetate = 40:1) to afford the target product 2-methyl-1,3-cyclopentanedione in 68% yield.

References

[1] Patent: CN105254483, 2016, A. Location in patent: Paragraph 0044

2-Methyl-1,3-cyclopentanedione Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Methyl-1,3-cyclopentanedione Suppliers

Americas 1 Belgium 3 China 206 Europe 3 Germany 10 India 15 Japan 3 Poland 3 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 18 United States 32 Global 298

Shandong Huasheng High-tech Industry Co., LTD

Tel: 18660771812
Email: 2103518043@qq.com
Country: China
ProdList: 83
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

More

Less

View Lastest Price from 2-Methyl-1,3-cyclopentanedione manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methyl-1,3-cyclopentanedione 765-69-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-10

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-Methyl-1, 3-Cyclopentanedione 765-69-5
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

Career Henan Chemical Co

Product: 2-Methyl-1,3-cyclopentanedione 765-69-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-05-24

765-69-5, 2-Methyl-1,3-cyclopentanedioneRelated Search:

Kresoxim-methyl Methanol Methylcyclohexane Methyl salicylate Basic Violet 1 Octamethylcyclotetrasiloxane Tribenuron methyl METSULFURON METHYL Hexamethylcyclotrisiloxane Cyclopropyl methyl ketone Acetylacetone 1,3-Cyclopentanedione 1,1,3,3,5,5-hexamethyl-1,3,5-trisilacyclohexane Octamethylcyclotetrasilazane 1,3-Cyclopentadiene Methylparaben METHYLCYCLOPENTADIENE DIMER Methyl acrylate

2-Methyl-1,3-cyclopentadione

2-METHYLCYCLOPENTAN-1,3-DIONE

2-METHYL-1,3-CYCLOPENTANEDIONE

METHYLCYCLE-D

2-Methylcyclopentane-1,3-dione,98%

1,3-Cyclopentanedione, 2-methyl-

2-METHYL-1,3-CYCLOPENTANEDIONE(METHYLCYCLO-D)

2-Methyl-1,3-cyclopentanediolne

2-Methylcyclopentane-1,3-dione

2-Methyl-1

2-Methyl-1,3-dioxocyclopentane

2-Methyl-1,3-cyclopentanedione 99%

2-Methyl-1,3-cyclopentanedione,98%

2-METHYL-1,3-CYCLOPENTANEDIONE FOR SYNTH

2-Methyl-1,3-cyclopentanedione, 97+%

2-Methylcyclopentan-1,3-dion

3-hydroxy-2-methyl-1-cyclopent-2-enone

2-Methyl-1,3-cyclopentanedione, 98%, for synthesis

2-Methyl-1,3-cyclopentanedione&gt

-1,3-cycL

2-METHYL-1,3-CYCLOPENTANEDIONE / CAS:765-69-5

765-69-5

1120-77-4

CH3C5H5O2

Building Blocks

Carbonyl Compounds

C3 to C6

Organic Building Blocks

Ketones

Miscellaneous

ketone

C3 to C6

Carbonyl Compounds

Ketones