ZLN-024 hydrochloride
- Product Name
- ZLN-024 hydrochloride
- CAS No.
- 1883548-91-1
- Chemical Name
- ZLN-024 hydrochloride
- Synonyms
- ZLN024 hydrochloride;ZLN-024 hydrochloride;ZLN 024 hydrochloride, 10 mM in DMSO;Inhibitor,AMP-activated protein kinase,ZLN-024,ZLN 024 hydrochloride,inhibit,ZLN024,ZLN 024,AMPK
- CBNumber
- CB52729380
- Molecular Formula
- C13H14BrClN2OS
- Formula Weight
- 361.68
- MOL File
- 1883548-91-1.mol
ZLN-024 hydrochloride Property
- solubility
- Soluble to 100 mM in DMSO
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 257174
- Product name
- ZLN 024 hydrochloride
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
- Product number
- Z485970
- Product name
- ZLN024Hydrochloride
- Packaging
- 250mg
- Price
- $1385
- Updated
- 2021/12/16
- Product number
- CS-3463
- Product name
- ZLN024hydrochloride
- Purity
- 98.54%
- Packaging
- 50mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- CS-3463
- Product name
- ZLN024hydrochloride
- Purity
- 98.54%
- Packaging
- 5mg
- Price
- $78
- Updated
- 2021/12/16
- Product number
- CS-3463
- Product name
- ZLN024hydrochloride
- Purity
- 98.54%
- Packaging
- 10mg
- Price
- $132
- Updated
- 2021/12/16
ZLN-024 hydrochloride Chemical Properties,Usage,Production
Uses
ZLN 024 Hydrochloride acts as an allosteric AMP-activated protein kinase activator, stimulating glucose uptake and fatty acid oxidation. Improved glucose tolerance and cholesterol content.
in vivo
C57BKS db/db mice are administered a 15 mg/kg/day dose of ZLN024 by daily gavage for 5 weeks; 250 mg/kg/day Metformin (Met) is used as a positive control. During the treatment period, there is no significant alteration in food intake and body weight compared with the vehicle group. After 4 weeks of treatment, ZLN024 improves glucose tolerance. ZLN024 reduces the fasting blood glucose by 15%. Liver tissue weight, triacylglycerol and the total cholesterol content are decreased[1].
IC 50
AMPK α2β2γ1: 0.13 μM (EC50); AMPK α1β1γ1: 0.42 μM (EC50); AMPK α2β1γ1: 0.95 μM (EC50)
storage
Store at +4°C
ZLN-024 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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