Bucladesine (calciuM salt)

Product Name: Bucladesine (calciuM salt)
CAS No.: 938448-87-4
Chemical Name: Bucladesine (calciuM salt)
Synonyms: DC2797 calcium salt;Bucladesine (calciuM salt);Dibutyryl-cAMP calcium salt;Bucladesine calcium (DC2797);Bucladesine calcium salt - Bio-X ?;Bucladesine (calciuM salt)，Bucladesinecalciumsalt
CBNumber: CB52735512
Molecular Formula: C18H26CaN5O8P
Formula Weight: 511.48
MOL File: 938448-87-4.mol

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Bucladesine (calciuM salt) Property

storage temp.: Store at -20°C
solubility: Water: 100 mg/mL (204.74 mM); DMSO: ≥ 100 mg/mL (204.74 mM)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B689320
Product name: BucladesineCalciumSalt
Packaging: 50mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BD164626
Product name: Bucladesine calcium
Packaging: 25mg
Price: $43
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NC11728
Product name: Bucladesine calcium salt
Packaging: 500mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-3558
Product name: Bucladesine(calcium)
Purity: 95.73%
Packaging: 50mg
Price: $78
Updated: 2021/12/16

ChemScene

Product number: CS-3558
Product name: Bucladesine(calcium)
Purity: 95.73%
Packaging: 100mg
Price: $96
Updated: 2021/12/16

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Bucladesine (calciuM salt) Chemical Properties,Usage,Production

Uses

Bucladesine Calcium Salt is a cell-permeable cAMP analogue that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway.

in vivo

Bucladesine (bilateral infusion of 10 mM or 100 mM) leads to a significant reduction in escape latency and travel distance (showing an improvement in spatial memory) compared to the control, as assesed by Morris water maze task in male rats. Bucladesine at 1 mM and 5 mM concentrations infused within minutes after 0.5 mg nicotine infusion improves spatial memory retention in male rats^[1].
Bucladesine (10 mM/side) combined with Nicotine (0.5 mM/side) results in a significant increase in the ChAT and VAChT immunoreactivity in CA1 regions, and increase in the optical density and amount of ChAT and VAChT immunostaining correlates with the decrease in escape latency and traveled distance in rats treated with Nicotine and low dose of Bucladesine^[2].
Bucladesine is absorbed very rapidly and almost completely when the aqueous solution is applied to the site where the skin has been excised. Bucladesine is absorbed rapidly but slower than in the full-thickness abrasion rat model in the case of stripped skin^[3].
Bucladesine (single or multiple administration of an emulsion containing 1.5%) is capable of significantly reducing the inflammatory oedema in the arachidonic acid induced ear oedema model in mice^[4].

IC 50

PKA; PDE

Bucladesine (calciuM salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Bucladesine (calciuM salt) manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Bucladesine calcium salt 938448-87-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 90.0%Min. HPLC
Supply Ability: 1000kg
Release date: 2022-11-07

938448-87-4, Bucladesine (calciuM salt)Related Search:

Bucladesine sodium

Bucladesine (calciuM salt)

DC2797 calcium salt

Dibutyryl-cAMP calcium salt

Bucladesine calcium (DC2797)

Bucladesine (calciuM salt)，Bucladesinecalciumsalt

Bucladesine calcium salt - Bio-X ?

938448-87-4

C18H24N5O8P12Ca