CO-1686 intermediate 1

Product Name: CO-1686 intermediate 1
CAS No.: 1374507-25-1
Chemical Name: CO-1686 intermediate 1
Synonyms: ROCI-005;CO-1686 intermediate 1;N-(3-((2-chloro-5-(trifluoromethyl)pyri midin-4-yl)amino)phenyl)acrylamide;N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide;N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide;2-Propenamide, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-
CBNumber: CB52737268
Molecular Formula: C14H10ClF3N4O
Formula Weight: 342.7
MOL File: 1374507-25-1.mol

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CO-1686 intermediate 1 Property

Boiling point:: 519.7±50.0 °C(Predicted)
Density: 1.476±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
pka: 13.21±0.70(Predicted)
InChI: InChI=1S/C14H10ClF3N4O/c1-2-11(23)20-8-4-3-5-9(6-8)21-12-10(14(16,17)18)7-19-13(15)22-12/h2-7H,1H2,(H,20,23)(H,19,21,22)
InChIKey: AXMHVOLJINONIM-UHFFFAOYSA-N
SMILES: C(NC1=CC=CC(NC2C(C(F)(F)F)=CN=C(Cl)N=2)=C1)(=O)C=C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A619735
Product name: N-(3-{[2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide
Packaging: 250mg
Price: $695
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0620699
Product name: N-(3-(2-CHLORO-5-(TRIFLUOROMETHYL)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $499.09
Updated: 2021/12/16

Chemenu

Product number: CM167724
Product name: N-(3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity: 95+%
Packaging: 5g
Price: $561
Updated: 2021/12/16

Crysdot

Product number: CD11269935
Product name: N-(3-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity: 97%
Packaging: 5g
Price: $600
Updated: 2021/12/16

Chemenu

Product number: CM167724
Product name: N-(3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity: 95+%
Packaging: 10g
Price: $935
Updated: 2021/12/16

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CO-1686 intermediate 1 Chemical Properties,Usage,Production

Uses

N-(3-{[2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide can be used as potent BTK and JAK3 dual inhibitors.

CO-1686 intermediate 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CO-1686 intermediate 1 Suppliers

China 34 United States 2 Global 36

Mashilabs (Shanghai) Co.,Ltd.

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Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

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SPIRO PHARMA

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Kaifute（Tianjin）Chemical Co., Ltd.

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Jinan elephant international trading co., LTD

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Amadis Chemical Company Limited

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Capot Chemical Co.,Ltd.

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Aikon International Limited

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1374507-25-1, CO-1686 intermediate 1Related Search:

CO-1686 intermediate 1

N-(3-((2-chloro-5-(trifluoromethyl)pyri midin-4-yl)amino)phenyl)acrylamide

N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide

N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide

ROCI-005

2-Propenamide, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-

1374507-25-1

C14H10ClF3N4O