Isoprenaline hydrochloride
- Product Name
- Isoprenaline hydrochloride
- CAS No.
- 51-30-9
- Chemical Name
- Isoprenaline hydrochloride
- Synonyms
- ISOPRENALINE HCL;ISOPROTERENOL HYDROCHLORIDE;isuprel;Isovon;Isomenyl;Mistarel;euspiran;isadrine;Proterno;proternol
- CBNumber
- CB5276844
- Molecular Formula
- C11H18ClNO3
- Formula Weight
- 247.72
- MOL File
- 51-30-9.mol
Isoprenaline hydrochloride Property
- Melting point:
- 165-175 °C (dec.)(lit.)
- Boiling point:
- 192°C (rough estimate)
- Density
- 1.2296 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- 2-8°C
- solubility
- Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
- form
- White solid
- color
- White to Off-White
- Water Solubility
- Soluble
- BRN
- 3917363
- Stability:
- Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
- InChIKey
- IROWCYIEJAOFOW-UHFFFAOYSA-N
- SMILES
- C1(=CC=C(O)C(O)=C1)C(O)CNC(C)C.Cl
- CAS DataBase Reference
- 51-30-9(CAS DataBase Reference)
- EPA Substance Registry System
- Isoproterenol hydrochloride (51-30-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- PHR2722
- Product name
- Isoproterenol Hydrochloride
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 250MG
- Price
- $200
- Updated
- 2024/03/01
- Product number
- BP205
- Product name
- Isoprenaline hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $257
- Updated
- 2024/03/01
- Product number
- 420355
- Product name
- Isoproterenol, Hydrochloride
- Purity
- Phenethylamine derivative.
- Packaging
- 100mg
- Price
- $54.7
- Updated
- 2024/03/01
- Product number
- 1351005
- Product name
- Isoproterenol hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 125mg
- Price
- $358
- Updated
- 2024/03/01
- Product number
- I0260
- Product name
- Isoproterenol Hydrochloride
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $74
- Updated
- 2024/03/01
Isoprenaline hydrochloride Chemical Properties,Usage,Production
Description
Isoprenaline hydrochloride is an FDA-approved injectable drug that is the hydrochloride form of isoprenaline and is used as a bronchodilator, adrenergic beta agonist, cardiotonic, and sympathomimetic. Selective beta-adrenergic agonist that increases cytoplasmic cAMP. promotes glycogenolysis and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit tracheal cells via nitric oxide production. In addition, it can be used as an inducer in an experimental rat model of induced myocardial infarction[1].
Chemical Properties
White or almost white, crystalline powder.
Uses
Isoproterenol is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.
Uses
Isoproterenol hydrochloride is used as a selective β-adrenergic agonist, increases cytosolic cAMP.
Definition
ChEBI: DL-Isoprenaline hydrochloride is a member of catechols.
brand name
Isuprel (Hospira); Isuprel (Sanofi Aventis); Vapo- ISO (Fisons).
General Description
Odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air.
Air & Water Reactions
May be sensitive to exposure to air and light. . Water soluble.
Reactivity Profile
An acid organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Health Hazard
SYMPTOMS: Symptoms of exposure to Isoprenaline hydrochloride may include tremors, nervous apprehension, palpitations of the heart, epigastric distress, cardiac arrhythmias, myocardial necrosis, cardiac arrest, tachycardia, headache, flushing of the skin, anginal pain, nausea, dizziness, weakness, and sweating.
Fire Hazard
Flash point data for Isoprenaline hydrochloride are not available. Isoprenaline hydrochloride is probably combustible.
Biological Activity
Standard selective β -adrenoceptor agonist; vasorelaxant and bronchodilator. Activation of β 2 receptors activates downstream PKA and ERK, and may stimulate NO-mediated endothelium-dependent smooth muscle relaxation. Active in vivo . Also available as part of the β -Adrenoceptor Agonist Tocriset™ and Mixed Adrenergic Tocriset™ .
Biochem/physiol Actions
β-adrenoceptor agonist; increases cytosolic cAMP.
storage
Store at RT
References
[1] FANG WANG. Fucoxanthin averts isoprenaline hydrochloride-induced myocardial infarction in rats[J]. Pharmacognosy Magazine, 2020, 16 1: 214-220. DOI:10.4103/pm.pm\_357\_19.
Isoprenaline hydrochloride Preparation Products And Raw materials
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View Lastest Price from Isoprenaline hydrochloride manufacturers
- Product
- Isoprenaline hydrochloride 51-30-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 20 tons
- Release date
- 2024-04-03
- Product
- Isoprenaline hydrochloride 51-30-9
- Price
- US $0.00/KG
- Min. Order
- 100g
- Purity
- 98%+
- Supply Ability
- 100kg
- Release date
- 2020-10-28
- Product
- Isoprenaline Hydrochloride 51-30-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99% HPLC
- Supply Ability
- 5 TON
- Release date
- 2023-07-07