ChemicalBook > CAS DataBase List > (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE

(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE

Product Name
(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE
CAS No.
1026-05-7
Chemical Name
(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE
Synonyms
ASISCHEM N44996;AKOS BBS-00005674;2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-aMine;4-Quinolinamine, 1,2,3,4-tetrahydro-2-methyl-N-phenyl-;Quinaldine,4-anilino-1,2,3,4-tetrahydro- (6CI,7CI,8CI);(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE;N-(2-METHYL-1,2,3,4-TETRAHYDRO-4-QUINOLINYL)-N-PHENYLAMINE;Propanedinitrile,2-(3-cyano-4,5,5-trimethyl-2(7H)-furanylidene)-
CBNumber
CB5278343
Molecular Formula
C16H18N2
Formula Weight
238.33
MOL File
1026-05-7.mol
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(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE Property

Melting point:
126 °C
Boiling point:
400.4±44.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
4.16±0.60(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ark Pharm
Product number
P000564070
Product name
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
Purity
95+%
Packaging
100mg
Price
$55
Updated
2021/12/16
Ark Pharm
Product number
P000564070
Product name
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
Purity
95+%
Packaging
250mg
Price
$88
Updated
2021/12/16
AK Scientific
Product number
7665AC
Product name
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
Packaging
250mg
Price
$212
Updated
2021/12/16
Ark Pharm
Product number
P000564070
Product name
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
Purity
95+%
Packaging
1g
Price
$220
Updated
2021/12/16
Matrix Scientific
Product number
080572
Product name
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
Packaging
500mg
Price
$252
Updated
2021/12/16
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(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE Chemical Properties,Usage,Production

Synthesis

15727-49-8

1026-05-7

General procedure for the synthesis of 2-methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine from 2-phenylaminopropionic acid: 2-phenylaminopropionic acid (66 mg, 0.4 mmol) and 4?molecular sieves (100 mg) were added to a 10 mL reaction vial, dried with an air pump, and then 200 μL of a reaction vial containing an organic photocatalyst, DPZ (0.28 mg 0.0008 mmol) in toluene solution. Subsequently, 4 mL of purified water was added, the reaction mixture was dried with chloroform, and the mouth of the flask was sealed with a rubber stopper and a balloon filled with dry air was inserted. The reaction flask was placed in a 25°C incubator and the reaction was stirred for 15 h under the illumination of two 1 W blue LEDs. Upon completion of the reaction, about 2/3 of the solvent was removed by distillation using a rotary evaporator. Purification by column chromatography (eluent: hexane/ethyl acetate, 60:30:1) afforded 2-methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine (39.1 mg, 82% yield) as a colorless oily liquid.

References

[1] Patent: CN108017579, 2018, A. Location in patent: Paragraph 0008; 0011; 0012

(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE Suppliers

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