6-CYANONICOTINIC ACID
- Product Name
- 6-CYANONICOTINIC ACID
- CAS No.
- 70165-31-0
- Chemical Name
- 6-CYANONICOTINIC ACID
- Synonyms
- 6-Cyanonicotinicaci;6-CYANONICOTINIC ACID;6-Cuanonicotinic acid;5-carboxypicolinonitrile;2-CYANO-5-CARBOXYPYRIDINE;6-Cyanonicotinic acid ,97%;6-Cyanonicotinic acid 95+%;N-(Pyridin-3-ylmethyl)ethanamine;3-Pyridinecarboxylicacid,6-cyano-;6-Cyano-pyridin-3-carboxylic acid
- CBNumber
- CB5278530
- Molecular Formula
- C7H4N2O2
- Formula Weight
- 148.12
- MOL File
- 70165-31-0.mol
6-CYANONICOTINIC ACID Property
- Melting point:
- 190-194 °C(lit.)
- Boiling point:
- 395.9±27.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in alcohol.
- form
- Oil
- pka
- 2.81±0.10(Predicted)
- color
- Clear Yellow
- BRN
- 4384027
- CAS DataBase Reference
- 70165-31-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- RIDADR
- 3439
- WGK Germany
- 3
- Hazard Note
- Harmful
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 656429
- Product name
- 6-Cyanopyridine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $194
- Updated
- 2025/07/31
- Product number
- C998373
- Product name
- 6-CyanonicotinicAcid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FC44821
- Product name
- 6-Cyanonicotinic acid
- Packaging
- 500mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 4H37-1-X1
- Product name
- 6-Cyanonicotinic acid
- Packaging
- 1g
- Price
- $141
- Updated
- 2021/12/16
- Product number
- FC44821
- Product name
- 6-Cyanonicotinic acid
- Packaging
- 1g
- Price
- $215
- Updated
- 2021/12/16
6-CYANONICOTINIC ACID Chemical Properties,Usage,Production
Uses
6-Cyanonicotinic acid, is used in medicine
Synthesis
2398-81-4
143-33-9
70165-31-0
The general procedure for the synthesis of 6-cyanonicotinic acid from oxonicotinic acid and sodium cyanide was as follows: to a 1.2 L DMF solution of oxonicotinic acid N-oxide (51 g, 0.37 mol) was added sodium cyanide (54 g, 1.1 mol), triethylamine (255 mL, 1.83 mol), and trimethylchlorosilane (185 mL). The reaction mixture was stirred at 110 °C for 10 h. After completion of the reaction, filtration was performed and the filtrate was concentrated. The residue was dissolved in 100 mL of 2N hydrochloric acid and extracted with dichloromethane. The organic layers were combined, concentrated and recrystallized from water to give 12 g (22% yield) of 6-cyanonicotinic acid.
References
[1] Synthesis, 1983, # 4, p. 316 - 319
[2] Chemical Communications, 2004, # 15, p. 1770 - 1771
[3] Patent: WO2003/101956, 2003, A1. Location in patent: Page 113; 114
[4] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 4, p. 385 - 389
6-CYANONICOTINIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-CYANONICOTINIC ACID manufacturers
- Product
- 6-CYANONICOTINIC ACID 70165-31-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-26
- Product
- 6-CYANONICOTINIC ACID 70165-31-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 6-CYANONICOTINIC ACID 70165-31-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09