2-CYANO-5-ETHOXYCARBONYLPYRIDINE

Product Name: 2-CYANO-5-ETHOXYCARBONYLPYRIDINE
CAS No.: 76196-79-7
Chemical Name: 2-CYANO-5-ETHOXYCARBONYLPYRIDINE
Synonyms: 6-Cyanonicotinic acid ethyl ester;5-ethoxycarbonyl-2-pyridinecarbonitrile;6-Cyano-3-pyridinecarboxylic acid ethyl ester;3-Pyridinecarboxylic acid, 6-cyano-, ethyl ester;2-CYANO-5-ETHOXYCARBONYLPYRIDINE ISO 9001：2015 REACH
CBNumber: CB11010070
Molecular Formula: C9H8N2O2
Formula Weight: 176.17
MOL File: 76196-79-7.mol

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2-CYANO-5-ETHOXYCARBONYLPYRIDINE Property

Melting point:: 56-57℃
Boiling point:: 125 °C(Press: 3 Torr)
Density: 1.21
storage temp.: Sealed in dry,Room Temperature
pka: -2.25±0.10(Predicted)
Appearance: Light yellow to brown Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

AstaTech

Product number: AR3383
Product name: ETHYL 6-CYANONICOTINATE
Purity: 95%
Packaging: 1G
Price: $47
Updated: 2026/04/30

AstaTech

Product number: AR3383
Product name: ETHYL 6-CYANONICOTINATE
Purity: 95%
Packaging: 5G
Price: $243
Updated: 2026/04/30

AstaTech

Product number: AR3383
Product name: ETHYL 6-CYANONICOTINATE
Purity: 95%
Packaging: 10G
Price: $374
Updated: 2026/04/30

TRC

Product number: E937238
Product name: Ethyl6-Cyanonicotinate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0118626
Product name: ETHYL 6-CYANOPYRIDINE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 5G
Price: $1420.65
Updated: 2021/12/16

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2-CYANO-5-ETHOXYCARBONYLPYRIDINE Chemical Properties,Usage,Production

Synthesis

14906-63-9

7677-24-9

76196-79-7

75358-90-6

To a solution of 3-ethoxycarbonylpyridine N-oxide dissolved in 330 mL of dichloromethane (DCM) was added trimethylmethylsilyl cyanide (TMSCN) (11.0 g, 65.9 mmol, 1.0 eq.) and dimethylcarbamoyl chloride (7.1 g, 65.9 mmol, 1.0 eq.) in that order. The reaction mixture was stirred at room temperature for 48 hours. Subsequently, the reaction mixture was adjusted to alkaline by slowly adding a 10% solution of potassium carbonate (K2CO3). The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford ethyl 6-cyanonicotinate (compound A, 5.7 g) and ethyl 2-cyanonicotinate (compound B, 3.5 g).

References

[1] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 2, p. 565 - 571
[2] Patent: WO2013/102142, 2013, A1. Location in patent: Paragraph 0141
[3] Patent: WO2013/102145, 2013, A1. Location in patent: Paragraph 0247
[4] Patent: US2015/344483, 2015, A1. Location in patent: Paragraph 0474; 0475

2-CYANO-5-ETHOXYCARBONYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYANO-5-ETHOXYCARBONYLPYRIDINE Suppliers

China 34 India 1 United Kingdom 2 United States 5 Global 42

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76196-79-7, 2-CYANO-5-ETHOXYCARBONYLPYRIDINERelated Search:

2-ACETONITRILPYRIDINE-6-CARBOXYLIC ACID EHTYL ESTER IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester Diethyl ethylmalonate Ethyl pyrazolo[1,5-a]pyriMidine-2-carboxylate 4,6-Dihydroxy-5-nitropyridine-3-carboxylic acid ethyl ester 5-BROMO-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 8-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester ethyl 2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate Ethyl 4-chloro-7-methoxyquinoline- 3-carboxylate ETHYL 6-BROMO-4-CHLORO-3-QUINOLINECARBOXYLATE 1H-Pyrazole-3-carboxylicacid,4-cyano-,ethylester(9CI) ethyl2-methylquinoline-6-carboxylate 4,6-DICHLORO-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER 6-CYANONICOTINIC ACID 2-CYANO-5-HYDROXYMETHYLPYRIDINE 2-CYANO-5-ETHOXYCARBONYLPYRIDINE

6-Cyano-3-pyridinecarboxylic acid ethyl ester

6-Cyanonicotinic acid ethyl ester

3-Pyridinecarboxylic acid, 6-cyano-, ethyl ester

5-ethoxycarbonyl-2-pyridinecarbonitrile

2-CYANO-5-ETHOXYCARBONYLPYRIDINE ISO 9001：2015 REACH

76196-79-7