Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester

Product Name: Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester
CAS No.: 427878-70-4
Chemical Name: Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester
Synonyms: Ethyl 4-hydroxy-5-Methylp...;ethyl 5-methyl-4-oxo-1,4-dihydropyrrolo[2,1-f][1,2,4]triazin...;Ethyl 4-hydroxy-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carboxylate;Ethyl 4-hydroxy-5-Methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate;5-methyl-4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate;ethyl 5-methyl-4-oxo-3H,4H-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate;Ethyl 1,4-dihydro-5-methyl-4-oxo-pyrrolo2,1-f1,2,4triazin-6-carboxylate;Ethyl 5-methyl-4-oxo-1,4-dihydropyrrolo[2,1-f][1,2,4]triazin-6-carboxylate;Ethyl 5-methyl-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-6-carboxylate;Ethyl 5-Methyl-4-oxo-1,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
CBNumber: CB72514085
Molecular Formula: C10H11N3O3
Formula Weight: 221.21
MOL File: 427878-70-4.mol

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Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester Property

storage temp.: Sealed in dry,Room Temperature
form: Powder
color: Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: E572330
Product name: ethyl5-methyl-4-oxo-1,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Packaging: 500mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-M1177
Product name: ethyl5-methyl-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-6-carboxylate
Packaging: 250mg
Price: $118
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0392585
Product name: ETHYL-5-METHYL-4-OXO-1,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $500.27
Updated: 2021/12/16

ChemScene

Product number: CS-M1177
Product name: ethyl5-methyl-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-6-carboxylate
Packaging: 1g
Price: $260
Updated: 2021/12/16

AK Scientific

Product number: Y9097
Product name: Ethyl5-methyl-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-6-carboxylate
Packaging: 250mg
Price: $296
Updated: 2021/12/16

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Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester Chemical Properties,Usage,Production

Synthesis

77287-34-4

427878-69-1

427878-70-4

1. The compound (CAS: 77287-34-4) was mixed with diethyl 1-amino-3-methyl-1H-pyrrole-2,4-dicarboxylate in formamide (8 mL) and 20 wt% acetic acid (2 g) was added. 2. The reaction mixture was heated at 120°C for 24 hours. 3. Upon completion of the reaction, it was cooled to room temperature and water (32 mL) was slowly added to precipitate the target product, ethyl 5-methyl-4-oxo-3,4-dihydropyrrolo[1,2-F][1,2,4]triazine-6-carboxylate. 4. The precipitated solid was collected by filtration and washed with ethyl acetate (EtOAc). 5. Drying gave the target compound as a yellow solid in 90% yield.

References

[1] Patent: US2006/235020, 2006, A1. Location in patent: Page/Page column 20
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 1, p. 4 - 16
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 21, p. 4774 - 4779
[4] Patent: US2006/3967, 2006, A1. Location in patent: Page/Page column 8
[5] Patent: US2006/229449, 2006, A1. Location in patent: Page/Page column 6

Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 1,4-dihydro-5-methyl-4-oxo-, ethyl ester Suppliers

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427878-70-4