2-Undecanone Property

Melting point:

11-13 °C(lit.)

Boiling point:

231-232 °C(lit.)

Density 

0.825 g/mL at 25 °C(lit.)

vapor density 

5.9 (vs air)

vapor pressure 

<1 mm Hg ( 20 °C)

refractive index 

n20/D 1.43(lit.)

FEMA 

3093 | 2-UNDECANONE

Flash point:

192 °F

storage temp. 

Store below +30°C.

form 

Liquid

color 

Clear colorless to light yellow

Odor

at 100.00 %. waxy fruity creamy fatty orris floral

Odor Type

fruity

Water Solubility 

INSOLUBLE

Merck 

14,6104

JECFA Number

296

BRN 

1749573

Dielectric constant

8.4000000000000004

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.

LogP

3.69 at 25℃

CAS DataBase Reference

112-12-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Undecanone(112-12-9)

EPA Substance Registry System

Methyl nonyl ketone (112-12-9)

Safety

Hazard Codes 

N

Risk Statements 

51/53-50/53

Safety Statements 

23-24/25-61-60

RIDADR 

UN3082

WGK Germany 

2

RTECS 

YQ2820000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29141990

Hazardous Substances Data

112-12-9(Hazardous Substances Data)

Toxicity

LD50 dermally in rabbits: >5 g/kg; LD50 orally in rats, mice: >5, 3.88 g/kg (Opdyke)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

2-Undecanone Chemical Properties,Usage,Production

Chemical Properties

2-undecanone, also known as methyl nonyl ketone, is a colorless to slightly yellow liquid and has a characteristic rue odor with a sweet flavor reminiscent of peach (on dilution). It naturally exists in Houttuynia cordata, bananas, strawberries, cloves, ginger and Rutaceae plants. The FEMA number is 3093, the FDA number is 172.515, and the CoE number is 150. methyl nonyl ketone is the active ingredient of Houttuynia cordata, mainly used in the production of medicines and fragrances, and is safer and more effective than DEET for mosquito repellents.

Physical properties

Methyl nonyl ketone (MNK) is a clear mobile liquid, with a strong characteristic smell at room temperature that presents a vapour pressure of 11.8 Pascals at 20° C. It has a very low solubility in water and high solubility in organic solvents such as n-heptane, p-xylene, 1,2-dichloroethane, methanol, acetone and ethyl acetate. MNK is not considered highly flammable or explosive or oxidizing.

Occurrence

Originally reported found in the essential oils of Ruta graveolens; subsequently was identified in the essential oils of Citrus limetta Risso., Fagara xanthoxyloides Lamm. and Litsea odorifera Val. (leaves); a method for the determination of methyl nonyl ketone in various rue species (Ruta montana, Ruta bracteosa) was devised; it is also present in the essential oils of Jaborandi (leaves), Hottuynia cordata, Phellodendron anaurense, Schizandar nigra Maxim., and in coconut and palm oils; also identified as the main constituent of the essential oil of Boronia ledifolia Gai; a 92% content level was reported in the essential oil of Ruta chalepensis. Also reported found in rabbiteye, blueberry, feijoa fruit, feijoa peel, peach, raspberry, fresh black berry, heated blackberry, strawberry jam, guava, allium, cloves, raw asparagus, shallot, roasted onion, ginger, Curcuma aeruginosa Roxb., Curcuma heyneana Val., banana, grapefruit, currants, peach, asparagus, shallot, onion, leek, chive, peas, potato, clove, ginger, pepper, many cheeses, wheaten bread, butter, milk, cream, yogurt, milk powder, goat and sheep milk, caviar, raw and smoked fatty fish, roast chicken, cooked beef, beef, chicken and pork fat, hop oil, beer, cognac, rum, sparkling wine, coffee, tea, roasted filberts and peanuts, coconut meat, milk and oil, passion fruit, mushroom, wild marjoram, starfruit, Brazil nut, cardamom, rice, buckwheat, corn oil, wort, elder flower, shrimp, crayfish, clam, maté and mastic gum leaf and fruit oil.

Uses

2-Undecanone may be used as an analytical reference standard for the quantification of the analyte in milk samples and Houttuynia cordata Thunb using gas chromatography (GC) technique.

Uses

In the compounding of some synthetic essential oils. As fragrance additive in soaps, detergents, creams, lotions, and perfume. As dog and cat repellant.

Preparation

Can be isolated from natural oils by fractional distillation; also by dry distillation of calcium acetate and calcium caprylate, or by boiling octylacetoacetic acid ethyl ester with and alcoholic KOH solution.

Definition

ChEBI: 2-Undecanone is a dialkyl ketone with methyl and nonyl as the two alkyl groups. It has a role as a rodenticide and a plant metabolite. It is a dialkyl ketone and a methyl ketone.

Aroma threshold values

Detection: 7 to 82 ppb

Taste threshold values

Taste characteristics at 30 ppm: waxy and fruity with creamy cheese notes

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 3411, 1982 DOI: 10.1016/S0040-4039(00)87629-7
The Journal of Organic Chemistry, 64, p. 2433, 1999 DOI: 10.1021/JO982239S

General Description

2-Undecanone is a naturally available nontoxic insect repellant, introduced as an alternative to insect repellants containing N,N-diethyl-meta-toluamide. It is isolated from the trichomes of wild tomatoes 2-Undecanone is also a volatile constituent, identified in milk and Houttuynia cordata Thunb?(HCT), a traditional Chinese medicine.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Taste: @ 10 ppm.

Safety Profile

Moderately toxic by ingestion. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fLt-e, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.

Synthesis

2-Undecanone's three synthesis methods is as follows:1) by oxidation of Undecanol-2.2) from Decanoic acid and Acetic acid, heated over Thorium oxide to 450℃.3) The isolation from Rue oil is of no commercial importance.