Norgestrel
- Product Name
- Norgestrel
- CAS No.
- 6533-00-2
- Chemical Name
- Norgestrel
- Synonyms
- sh850;wy3707;sh70850;monovar;Neogest;Ovrette;fh122-a;NORPLANT;OVRETTE(R);NORGESTREL
- CBNumber
- CB2752440
- Molecular Formula
- C21H28O2
- Formula Weight
- 312.45
- MOL File
- 6533-00-2.mol
Norgestrel Property
- Melting point:
- 239-241 °C(lit.)
- Boiling point:
- 392.36°C (rough estimate)
- Density
- 1.0697 (rough estimate)
- refractive index
- 1.4900 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly)
- pka
- 13.09±0.40(Predicted)
- color
- Crystals from diethyl ether-hexane
- InChIKey
- WWYNJERNGUHSAO-XUDSTZEESA-N
- CAS DataBase Reference
- 6533-00-2(CAS DataBase Reference)
- EPA Substance Registry System
- Norgestrel (6533-00-2)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-40
- Safety Statements
- 22-36
- WGK Germany
- 3
- RTECS
- JF8259000
- HS Code
- 2937230000
- Hazardous Substances Data
- 6533-00-2(Hazardous Substances Data)
- Toxicity
- LD50 oral in rat: 5010mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PHR2487
- Product name
- Norgestrel
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 200MG
- Price
- $253
- Updated
- 2024/03/01
- Product number
- N1250000
- Product name
- Norgestrel
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- n1250000
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 1472000
- Product name
- Norgestrel
- Packaging
- 125mg
- Price
- $358
- Updated
- 2024/03/01
- Product number
- 10006319
- Product name
- Norgestrel
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $25
- Updated
- 2024/03/01
- Product number
- 10006319
- Product name
- Norgestrel
- Purity
- ≥95%
- Packaging
- 500mg
- Price
- $107
- Updated
- 2024/03/01
Norgestrel Chemical Properties,Usage,Production
Description
Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives.
Chemical Properties
White Solid
Uses
Progestogen; oral contraceptive. The bioactive enantiomer is levorotatory
Uses
A metabolite of Norgestrel.
Uses
Protected D-(-)-Norgestrel
Uses
A glucuronide metabolite of Levonorgestrel.
Uses
An intermediate to the glucuronide metabolite of Levonorgestrel.
Uses
analgesic, antipyretic
Uses
It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.
Definition
ChEBI: Levonorgestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin, a synthetic oral contraceptive and a female contraceptive drug. It is functionally related to a norgestrel. It is an enantiomer of a dexonorgestrel.
brand name
Ovrette (Wyeth).
General Description
Norgestrel, (17α)-(±)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, and levonorgestrel, (17α)-(-)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one,have a C13 ethyl group instead of the C13 methyl but haveprogestational properties similar to those of norethindrone,with decreased androgenic effects. The ethyl group apparentlyprovides unfavorable steric interactions with the ARthat reduce the affinity compared with that with the PRs.Norgestrel is a racemic mixture, while levonorgestrel is thesingle active levorotatory enantiomer. Norgestrel is usedonly in oral contraceptives. Levonorgestrel is used in bothoral combination birth control products and polymeric implantsthat provide contraception for up to 5 years.
Safety Profile
Human reproductive effects byingestion and implant: menstrual cycle changes ordisorders and female fertility index changes. Anexperimental teratogen. Experimental reproductiveeffects. Questionable carcinogen with experimentalneoplastigenic data. An o
Norgestrel Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Norgestrel manufacturers
- Product
- Norgestrel 6533-00-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- Levonorgestrel 6533-00-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-11-03
- Product
- Norgestrel 6533-00-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 50g
- Purity
- 98%-102%;USP
- Supply Ability
- 10KG
- Release date
- 2021-06-18