FOXO4
- Product Name
- FOXO4
- Chemical Name
- FOXO4
- Synonyms
- AFX;AFX1;Afxh;MLLT7;FOXO4;forkhead domain AFX1;Forkhead box protein O4;Anti-FOXO4, C-Terminal antibody produced in rabbit;ANTI-MLLT7(N-TERMINAL) antibody produced in rabbit
- CBNumber
- CB52896187
- Formula Weight
- 0
- MOL File
- Mol file
FOXO4 Property
- storage temp.
- -20°C
N-Bromosuccinimide Price
- Product number
- F9049-45PK
- Product name
- FOXO4
- Packaging
- 1mg
- Price
- $262
- Updated
- 2021/12/16
- Product number
- 481316
- Product name
- FOXO4
- Packaging
- 100ul
- Price
- $499
- Updated
- 2021/12/16
- Product number
- orb530437
- Product name
- FOXO4
- Packaging
- 10μg
- Price
- $831.3
- Updated
- 2021/12/16
FOXO4 Chemical Properties,Usage,Production
Description
Forkhead box O4 (FOXO4) is a member of the FOXO family that regulates a number of genes involved in metabolism, cell cycle, apoptosis, and cellular homeostasis via transcriptional activity. It also mediates cell responses to oxidative stress and treatment with antitumor agents. The expression of FOXO4 is repressed by microRNAs in multiple cancer cells, while FOXO4 function is regulated by post-translational modifications and interaction with other proteins. The deregulation of FOXO4 is closely linked to the progression of several types of cancer, senescence, and other diseases[1].
Biological Activity
FOXO4 is a member of the forkhead family of transcription factors in O subclass, which is characterized by a winged helix domain used for DNA binding. There are 4 members of the FOXO family, including FOXO1, FOXO3, and FOXO6. Their activity is modified by many post translational activities, such as phosphorylation, ubiquitination, and acetylation.
Physiological effects
FOXO4 binding affinity for DNA is altered, allowing for FOXO4 to regulate many cellular pathways including oxidative stress signaling, longevity, insulin signaling, cell cycle progression, and apoptosis.
References
[1] Wen Liu, Bing Luo, Yong Li. “Current perspective on the regulation of FOXO4 and its role in disease progression.” Cellular and Molecular Life Sciences 217 1 (2020): 651–663.
FOXO4 Preparation Products And Raw materials
Raw materials
Preparation Products
FOXO4 Suppliers
- Tel
- 025-58361106-805 15951641583
- Fax
- 025-58361106-806
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- China
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View Lastest Price from FOXO4 manufacturers
- Product
- FOXO4
- Price
- US $10.00/box
- Min. Order
- 1box
- Purity
- 99.99
- Supply Ability
- 1000000box
- Release date
- 2026-01-23
- Product
- FOXO4
- Price
- US $100.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100kg
- Release date
- 2023-12-14
- Product
- FOXO4
- Price
- US $56.00-44.00/Box
- Min. Order
- 1Box
- Purity
- 99%
- Supply Ability
- 1000 boxs
- Release date
- 2024-05-29