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FMOC-LYS(ALOC)-OH

Product Name
FMOC-LYS(ALOC)-OH
CAS No.
146982-27-6
Chemical Name
FMOC-LYS(ALOC)-OH
Synonyms
FMOC-LYS(ALOC)-OH;Fmoc-L-Lys(Alloc);FMOC-LYS(ALLOC)-OH;FMOC-L-LYS(ALOC)-OH;FMOC-L-LYS(ALLOC)-OH;FMOC-LYSINE(ALOC)-OH;FMOC-N-E-ALLOC-L-LYSINE;nα-fmoc-nε-alloc-l-lysine;Fmoc-Lys(Alloc)-OH 98%min;FMOC-N-EPSILON-ALLOC-L-LYSINE
CBNumber
CB5292327
Molecular Formula
C25H28N2O6
Formula Weight
452.5
MOL File
146982-27-6.mol
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FMOC-LYS(ALOC)-OH Property

Melting point:
87-91°C
Boiling point:
689.7±55.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.88±0.21(Predicted)
form 
Solid
color 
White to off-white
optical activity
[α]20/D 12±1°, c = 1% in DMF
BRN 
5893081
InChIKey
OJBNDXHENJDCBA-QFIPXVFZSA-N
SMILES
C(O)(=O)[C@H](CCCCNC(OCC=C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
146982-27-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2924 29 70
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52124
Product name
Fmoc-Lys(Alloc)-OH
Purity
Novabiochem?
Packaging
5G
Price
$95.9
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52124
Product name
Fmoc-Lys(Alloc)-OH
Purity
Novabiochem?
Packaging
25g
Price
$545
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52124
Product name
Fmoc-Lys(Alloc)-OH
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
100 g
Price
$2050
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52124
Product name
Fmoc-Lys(Alloc)-OH
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
100 g
Price
$2050
Updated
2025/07/31
Sigma-Aldrich
Product number
47583
Product name
Fmoc-Lys(Alloc)-OH
Purity
≥95.0% (HPLC)
Packaging
1g
Price
$44.05
Updated
2025/07/31
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FMOC-LYS(ALOC)-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

FMOC-LYS(ALOC)-OH is most often used in peptide synthesis.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

105047-45-8

2937-50-0

146982-27-6

The general procedure for the synthesis of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-[(2-propenyloxy)carbonyl]-L-lysine from (S)-2-((9H-fluoren-9-ylmethoxy)methoxy)carbonyl)amino)-6-aminohexanoic acid and allyl chloroformate was as follows: Example L1c: 25 g (61.7 mmol) of (S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid was dissolved in 275 mL of dioxane and mixed with 25 mL of 25% potassium carbonate solution, followed by the addition of 6.55 mL of allyl chloroformate. The reaction mixture was stirred at 23°C for 20 hours. Upon completion of the reaction, the reaction solution was diluted with water and extracted with methyl tert-butyl ether. The aqueous phase was separated, acidified with 2N hydrochloric acid and extracted with dichloromethane several times. The dichloromethane phase was combined and dried with sodium sulfate. After filtration, the solvent was removed under reduced pressure to afford 26.3 g (58.1 mmol, 94%) of N-[(9H-fluoren-9-methoxy)carbonyl]-N'-[(2-propenyloxy)carbonyl]-L-lysine, and the product could be used for subsequent reactions without further purification.

References

[1] Patent: US2005/234247, 2005, A1. Location in patent: Page/Page column 15
[2] ChemBioChem, 2010, vol. 11, # 8, p. 1083 - 1092

FMOC-LYS(ALOC)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-LYS(ALOC)-OH Suppliers

China 237 Europe 3 France 1 Germany 4 India 7 Japan 4 Switzerland 2 United Kingdom 5 United States 25 Global 288
Globe Chemie
Tel
--
Fax
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Email
info@globechemie.co.in
Country
India
ProdList
293
Advantage
50
Central Drug House(P) Ltd.
Tel
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Fax
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Email
sales@cdhfinechemical.com
Country
India
ProdList
6157
Advantage
58
A.J Chemicals
Tel
--
Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
CHEMSWORTH
Tel
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Fax
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Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
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View Lastest Price from FMOC-LYS(ALOC)-OH manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
Fmoc-Lys(Alloc)-OH 146982-27-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-10-09
Shanghai Joiny Pharmaceutical Co.,LTD
Product
N-Fmoc-N'-allyoxycarbonyl-L-lysine 146982-27-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2025-09-22
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Lys(Alloc)-OH 146982-27-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2024-03-06

146982-27-6, FMOC-LYS(ALOC)-OHRelated Search:

Tert-butyl bis(2-chloroethyl)carbamate Fmoc-S-acetamidomethyl-L-cysteine Fmoc-D-Lys(ipr,Boc)-OH FMOC-LYS(MCA)-OH N(ALPHA)-FMOC-N(EPSILON)-DABCYL-L-LYSINE Fmoc-Lys(nicotinoyl)-OH FMOC-LYS(5-FAM)-OH Fmoc-HoLys(N3)-OH Nalpha-FMOC-L-Tryptophan FMOC-D-Lys(BOC)-OH Fmoc-O-trityl-L-serine Boc-Lys(Boc)-OH Fmoc-Trp(Boc)-OH Fmoc-Lys(Boc)-OH Fmoc-D-Trp(Boc)-OH Fmoc-O-tert-butyl-D-threonine L-Fmoc-Aspartic acid alpha-tert-butyl ester FMOC-L-TYR(ALL)-OH

  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-ALLYL-OXYCARBONYL-L-LYSINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-ALLYLOXYCARBONYL-L-LYSINE
  • N-ALPHA-FMOC-N-EPSILON-ALLYLOXYCARBONYL-L-LYSINE
  • N-ALPHA-FMOC-N-EPSILON-ALLOC-L-LYSINE
  • FMOC-LYS(ALLOC)-OH
  • FMOC-LYS(ALOC)-OH
  • FMOC-LYSINE(ALOC)-OH
  • FMOC-L-LYS(ALLOC)-OH
  • FMOC-L-LYS(ALOC)-OH
  • FMOC-N-EPSILON-ALLOC-L-LYSINE
  • FMOC-N-EPSILON-ALLYLOXYCARBONYL-L-LYSINE
  • N-α-Fmoc-N-ε-allyoxycarbonyl-L-lysine
  • nα-fmoc-nε-alloc-l-lysine
  • FMOC-(ALLYLOXYCARBONYL)-LYSINE
  • FMOC-N-E-ALLOC-L-LYSINE
  • N-.ALPHA.-FMOC-N-.EPSILON.-ALLYOXYCARBONYL-L-LYSINE
  • N-Fmoc-N-allyloxycarbonyl L-lysine
  • N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(2-propen-1-yloxy)carbonyl]-L-Lysine
  • FMoc-Lys(Alloc)-OH N-α-FMoc-N-ε-allyoxycarbonyl-L-lysine
  • (2S)-6-{[(allyloxy)carbonyl]aMino}-2-{[(9H-fluoren-9-ylMethoxy)carbonyl]aMino}hexanoic acid
  • N^e-Allyloxycarbonyl-N^a-FMoc-L-lysine, 95%
  • (S)-2-((((9H-fFuoren-9-yl)Methoxy)carbonyl)aMino)-6-(((allyloxy)carbonyl)aMino)hexanoic acid
  • L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(2-propen-1-yloxy)carbonyl]-
  • Fmoc-Lys(Alloc)-OH >=95.0% (HPLC)
  • Nα-Fmoc-Nε-allyloxycarbonyl-L-lysine≥ 99.9% (HPLC, Chiral purity)
  • Nepsilon-Allyloxycarbonyl-Nalpha-Fmoc-L-lysine
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl L-Lys(Alloc)-OH
  • N2-Fmoc-N6-[(allyloxy)carbonyl]-L-lysine
  • Fmoc-L-Lys(Alloc)
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-{[(prop-2-en-1-yloxy)carbonyl]amino}hexanoic acid
  • N6-[(Allyloxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
  • Nepsilon-Alloc-Nalpha-Fmoc-L-lysine
  • Nα-Fmoc-Nε-allyloxycarbonyl-L-lysine
  • N - [(9h fluorene-9-methoxy) carbonyl] - n '- [(2-propenoxy) carbonyl] - l-lysine
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((allyloxy)carbonyl)amino)hexanoic acid
  • Fluorene methoxycarbonyl-lysine(ALLOC)
  • Fmoc-Lys(Alloc)-OH 98%min
  • 146982-27-6
  • 1146982-27-6
  • Analytical Standards
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