1-METHYL-1H-INDOLE-5-CARBALDEHYDE
- Product Name
- 1-METHYL-1H-INDOLE-5-CARBALDEHYDE
- CAS No.
- 90923-75-4
- Chemical Name
- 1-METHYL-1H-INDOLE-5-CARBALDEHYDE
- Synonyms
- 1-Methylindolecarbaldehyde;5-Formyl-1-methyl-1H-indole;1-Methylindole-5-carbaldehyde;1-Methylindole-5-carboxaldehyde;1-METHYL-1H-INDOLE-5-CARBALDEHYDE;1-METHYL-1H-INDOLE-5-CARBOXALDEHYDE;1H-Indole-5-carboxaldehyde, 1-methyl-;1-Methyl-1H-indole-5-carboxaldehyde97%;1-Methyl-1H-indole-5-carboxaldehyde 97%;1-Methyl-1H-indole-5-carboxaldehyde
- CBNumber
- CB5294013
- Molecular Formula
- C10H9NO
- Formula Weight
- 159.18
- MOL File
- 90923-75-4.mol
1-METHYL-1H-INDOLE-5-CARBALDEHYDE Property
- Melting point:
- 84-85.5
- Boiling point:
- 318.7±15.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- Appearance
- Off-white to light yellow Solid
- Sensitive
- Air & Moisture Sensitive
- InChI
- InChI=1S/C10H9NO/c1-11-5-4-9-6-8(7-12)2-3-10(9)11/h2-7H,1H3
- InChIKey
- XIVDZBIBWGQOTI-UHFFFAOYSA-N
- SMILES
- N1(C)C2=C(C=C(C=O)C=C2)C=C1
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36
- WGK Germany
- 3
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 774561
- Product name
- 1-Methyl-1H-indole-5-carboxaldehyde
- Purity
- 97%
- Packaging
- 500mg
- Price
- $140.7
- Updated
- 2025/07/31
- Product number
- M219168
- Product name
- 1-Methyl-1H-indole-5-carbaldehyde
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- CS-0061753
- Product name
- 1-Methyl-1H-indole-5-carbaldehyde
- Purity
- 98.89%
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- OR9157
- Product name
- 1-Methyl-1H-indole-5-carboxaldehyde
- Purity
- 97%
- Packaging
- 250mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- OR9157
- Product name
- 1-Methyl-1H-indole-5-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
1-METHYL-1H-INDOLE-5-CARBALDEHYDE Chemical Properties,Usage,Production
Synthesis
1196-69-6
74-88-4
90923-75-4
To a solution of 5-indolecarboxaldehyde (1.0 g, 6.9 mmol) in N,N-dimethylformamide (DMF, 15 mL) was added sodium hydride (303 mg, 60% oil dispersion, 7.59 mmol) in one portion. The reaction mixture was stirred at room temperature for 30 minutes. Subsequently, iodomethane (1.96 g, 13.8 mmol) was added to the reaction system and the mixture was continued to stir overnight. Upon completion of the reaction, ethyl acetate (200 mL) was added to dilute the reaction mixture, and the organic phase was washed sequentially with water (3 x 20 mL) and saturated saline (25 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated to afford 1-methyl-1H-indole-5-carbaldehyde as an orange oil (1.0 g, 91% yield). The product was characterized by 1H NMR (200 MHz, CDCl3): δ 10.05 (s, 1H), 8.09 (s, 1H), 7.90-7.80 (m, 1H), 7.35-7.15 (m, 2H), 6.85-6.80 (m, 1H), 3.95 (s, 3H).
References
[1] Patent: WO2004/52890, 2004, A1. Location in patent: Page 91-92
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2060 - 2079
[3] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 167 - 183
[4] Patent: US2005/209274, 2005, A1. Location in patent: Page/Page column 27
[5] Journal of Organometallic Chemistry, 2011, vol. 696, # 5, p. 1072 - 1083
1-METHYL-1H-INDOLE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-METHYL-1H-INDOLE-5-CARBALDEHYDE manufacturers
- Product
- 1-METHYL-1H-INDOLE-5-CARBALDEHYDE 90923-75-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-19