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TMPYP

Product Name
TMPYP
CAS No.
36951-72-1
Chemical Name
TMPYP
Synonyms
TMPY;TMPYP;TMP 1363;TMPyP [=αTMPyP4 tosylate;TMPyP[=α, β,γTMP-1363 tetratosylate;TMPYP ISO 9001：2015 REACH;TMPYP,ultra-highsensitivespectr;Tetrakismethylpiridiniumylporphine
CBNumber
CB5294316
Molecular Formula
C72H66N8O12S4
Formula Weight
1363.6
MOL File
36951-72-1.mol
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TMPYP Property

Melting point:
>300℃
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
water: soluble50MM(lit.)
form 
Purple solid
color 
Dark red to Dark purple to Dark blue
Water Solubility 
Soluble to 50 mM in water
λmax
421 nm
BRN 
6049195
Stability:
Hygroscopic, Light Sensitive
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37
WGK Germany 
3
F 
3-8-10
HS Code 
2933.99.9701
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
323497
Product name
5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
Purity
Dye content 97 %
Packaging
100mg
Price
$91.2
Updated
2023/06/20
Sigma-Aldrich
Product number
323497
Product name
5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
Purity
Dye content 97 %
Packaging
250mg
Price
$193
Updated
2023/06/20
TCI Chemical
Product number
A5014
Product name
TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate][Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
Purity
>98.0%(N)
Packaging
1g
Price
$318
Updated
2024/03/01
TCI Chemical
Product number
A5014
Product name
TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate][Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
Purity
>98.0%(N)
Packaging
100mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
18474
Product name
TMPyP4 (tosylate)
Purity
≥95%
Packaging
50mg
Price
$37
Updated
2024/03/01
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TMPYP Chemical Properties,Usage,Production

Uses

TMPyP4 is a potent inhibitor of telomerase activity.

Definition

ChEBI: An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.

General Description

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p toluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O2 luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.

Biological Activity

Cell permeable: no', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 6.5 μM inhibiting human telomerase

storage

Store at +4°C

TMPYP Preparation Products And Raw materials

Raw materials

Preparation Products

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TMPYP Suppliers

Americas 1 China 87 Europe 3 Germany 4 India 5 Japan 2 South Korea 1 Switzerland 1 United Kingdom 3 United States 18 USA 1 Global 126
MedChemexpress LLC
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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Alfa Chemistry
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1-516-927-0118
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Info@alfa-chemistry.com
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United States
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24072
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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32161
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
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sales@aladdinsci.com
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58
ApexBio Technology
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Abcam
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Cayman Chemical Company
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cayman@caymanchem.com
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United States
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United States Biological
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MedChemExpress
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Combi-Blocks Inc.
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Riedel-de Haen AG
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TCI America
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Frontier Scientific, Inc.
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Matrix Scientific
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MP Biomedicals, Inc.
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View Lastest Price from TMPYP manufacturers

Dideu Industries Group Limited
Product
TMPYP 36951-72-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-27

36951-72-1, TMPYPRelated Search:

TPPS 5,10,15,20-tetrakis(4-ethynylphenyl)-21H,23H-Porphine meso-Tetra (p-bromophenyl) porphine TMPYP2 TMPYP4 Pd(II)TMPyP MN(III)TMPYP 5,10,15,20-TETRA(4-PYRIDYL)-21H,23H-PORPHINE Pyridine methanesulfonate PORPHINE 1 4-DIMETHYLPYRIDINIUM P-TOLUENESULFONA& TMPYP Pyridinium p-Toluenesulfonate

  • 5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate
  • TMPY
  • TMPYP
  • 5,10,15,20-TETRAKIS-(N-METHYL-4-PYRIDYL)-21,23H-PORPHYRIN TETRATOSYLATE
  • 5,10,15,20-TETRAKIS (1-METHYL-4-PYRIDINIO) PORPHINE TETRA (P-TOLUENESULFONATE)
  • 5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDINIO)-PORPHYRIN TETRA(P-TOLUENESULFONATE)
  • 5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDINIO)PORPHYRIN TETRA(TOLUENE-4-SULFONATE)
  • 5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDYL)-21H,23H-PORPHINE, TETRA-P-TOSYLATE SALT
  • ALPHA,BETA,GAMMA,DELTA-TETRAKIS(1-METHYLPIRIDINIUM-4-YL)PORPHINE P-TOLUENESULFONATE
  • ALPHA,BETA,GAMMA,DELTA-TETRAKIS(1-METHYLPYRIDINIUM-4-YL)PORPHINE P-TOLUENESULFONATE
  • MESO-TETRA-(1-METHYL-4-PYRIDINIO)PORPHYRIN TETRATOSYLATE
  • MESO-TETRA(4-N-METHYL-PYRIDYL)PORPHYRIN
  • MESO-TETRA (N-METHYL-4-PYRIDYL) PORPHINE TETRA TOSYLATE
  • MESO-TETRA(N-METHYL-4-PYRIDYL)PORPHINE TETRATOSYLATE SALT
  • meso-Tetra(4-N-methylpyridyl)porphyrine tetratosylate
  • TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals
  • TMPyP4 tosylate
  • 5,10,15,20-Tetrakis(1-Methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) Dye content 97 %
  • 5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,22-dihydroporphyrin
  • -Tetrakis(1-methylpyridinium-4-yl)porphyrin <i>p</i>-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
  • TMPyP [=&alpha
  • TMPyP[=α, β,&gamma
  • meso-tetrakis(N-methyl-4-pyridyl)porphine tetrakis(p-toluenesulfonate)
  • TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate]
  • 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetra(p-toluenesulfonate)
  • 5,10,15,20-tetrakis(1-methyl-4-pyridyl)-21H,23H-P
  • meso-tetra-(4-N-methyl-pyridyl)*porphine tetratos
  • tetrakis(1-me-4-pyridinio)porphyrin tetra tol-4-sulfona
  • Tetrakismethylpiridiniumylporphine
  • TMPyP [=alpha,?gamma,delta-Tetrakis(1-methylpiridinium-4-yl)porphine p-toluenesulfonate]
  • MESO-TETRA-(4-N-METHYL-PYRIDYL)*PORPHINE TETRATOSYL
  • TMPYP,ultra-highsensitivespectr
  • 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphine,tetrakis(p-toluenesulfonate)
  • TMPYP [ALPHA,SS,GAMMA,DELTA-TETRAKIS(1-METHYLPIRIDINIUM-4-YL)PORPHINE P-TOLUENESULFONATE]
  • 5,10,15,20-TETRAKIS(N-METHYLPYRIDINIUM-4-YL)-21H,23H-PORPHINE TETRAKIS(P-TOLUENESULFONATE) (TMPYP)
  • 5,10,15,20-Tetrakis-(4-N-methylpyridyl)-porphine tetrakis-(4-toluenesulfona
  • TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphine p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
  • TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate]
  • alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate
  • TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
  • tetrakis(1-methyl-4-pyridyl)-21H,23H-porphine p-tosylate
  • TMPyP, meso-Tetra(N-methyl-4-pyridyl)porphine tetratosylate salt
  • TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate][Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]&gt
  • TMP 1363
  • TMPYP ISO 9001：2015 REACH
  • TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate
  • TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
  • TMP-1363 tetratosylate
  • α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate
  • TMPyP 4,G-quadruplex,inhibit,TMPyP-4,TMP1363,TMP-1363,TMPyP4 tosylate,TMPyP-4 tosylate,Inhibitor,Telomerase,TMPyP4
  • 5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphyrin tetra(p-toluenesulphonate)
  • TMPyP4 tosylate, Telomerase inhibitor
  • 36951-72-1
  • C72H66N8O12
  • C72H66N8O12S4
  • C72H74N8O12S4
  • C44H38N84C7H7O3S
  • Detection