Homoarginine

ChemicalBook > CAS DataBase List > Homoarginine

Product Name: Homoarginine
CAS No.: 156-86-5
Chemical Name: Homoarginine
Synonyms: C01924;l-lysin;H-HAR-OH;(3βH-HOARG-OH;HOMOARGININE;H-HOMOARG-OH;L-HomoArg-OH;L-HOMOARGININE;H-HOMOARGININE
CBNumber: CB5298985
Molecular Formula: C7H16N4O2
Formula Weight: 188.23
MOL File: 156-86-5.mol

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Homoarginine Property

Melting point:: 207-209 °C
Boiling point:: 376.3±52.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 2.52±0.24(Predicted)
color: White to off-white
CAS DataBase Reference: 156-86-5(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: H585008
Product name: Homoarginine
Packaging: 10g
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-W008385
Product name: H-HoArg-OH
Purity: ≥98.0%
Packaging: 100g
Price: $278
Updated: 2021/12/16

Chem-Impex

Product number: 03989
Product name: L-Homoarginine
Purity: ≥ 99% (Assay)
Packaging: 5G
Price: $30
Updated: 2021/12/16

Activate Scientific

Product number: AS92343
Product name: L-Homoarginine
Purity: 95% ee
Packaging: 5G
Price: $99
Updated: 2021/12/16

ChemPep

Product number: 180132
Product name: H-HoArg-OH
Packaging: 5g
Price: $142
Updated: 2021/12/16

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Homoarginine Chemical Properties,Usage,Production

Description

Homoarginine and 1-hydroxyhomoarginine were originally detected in significant concentration in the seeds of many Lathyrus species (Bell, 1962a,b; 1963). Homoarginine was isolated from the seeds of L. cicera (Bell, 1962b) and L. sativus (Rao et al., 1963). The hydroxy compound was obtained from the seeds of L. tingitanus (Bell, 1964). The comparative distribution of guanidino compounds in the seeds of two genus of the Papilionoideae, Lathyrus and Vicia, exhibits interesting features (Bell and Tirimanna, 1964). For example, the genus Lathyrus stores predominantly the C7 amino acids homoarginine, y-hydroxyhomoarginine and the related compound lathyrine, while the genus Vicia stores relatively high concentrations of canavanine and of the C6 amino acids arginine and y-hydroxyarginine. Apart from plants, homoarginine was found in small amounts in human body fluids ,. urine (Armstrong, 1967), serum (Matsumoto et al., 1976a) and cerebrospinal fluid (Mori et al., 1981b) and in mammalian brain (Mori et al., 1978, 1979 ). Increased urinary excretion was reported in hyperlysinemia (Armstrong and Robinow, 1967) and citrullinemia (Scott-Emuakpor et al., 19(2).
Homoarginine may be formed in mammals from lysine, by a homologous urea cycle in which arginine is replaced by lysine (Ryan and Wells, 1964; Scott-Emuakpor et al., 19(2). The excretion of homocitrulline and homoarginine in urine following administration of lysine to children supports this theory (Buergi et al., 1966). The biosynthesis of homoarginine has not been examined in plants, but y-hydroxyhomoarginine is synthesized from homoarginine in Lathyrus seeds (Bell, 1964). Subsequently both compounds have been identified as the precursors of the cyclic guanidino derivative, lathyrine, also present in Lathyrus seeds (Bell and Przybylska, 1965). Homoarginine and y-hydroxyhomoarginine probably serve as nitrogen reserves in Lathyrus seeds.
Inhibition of growth by homoarginine has been reported In various microorganisms (Walker, 1955; Rao et al., 1963).
gama-Hydroxyhomoarginine lactone isolated from the seeds of L. tingitanus (Bell, 1964) probably results from the cyclization of the open chain compound under acidic conditions.

Chemical Properties

White to off-white powder

Uses

Homoarginine is an inhibitor of human arginase activity.

Uses

Homoarginine as marker for exogenous protein
Absorption and secretion of free homoarginine in the intestine: when 9 mmol homoarginine were infused into the proximal part of the jejunum, there was a 99.9% disappearance of the free amino acid homoarginine up to the ileum. In addition, following the infusion of 9 mmol homoarginine into the vena jugularis less than 0.2% of the infused homoarginine appeared in the intestine.
We concluded from these data that with the homoarginine method endogenous protein in the chyme of the intestine can be distinguished from the food protein as homoarginine is not incorporated into endogenous secreta and free homo arginine is completely absorbed.

Definition

ChEBI: An L-lysine derivative that is the L-enantiomer of homoarginine.

Homoarginine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Homoarginine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Homoarginine 156-86-5
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: L-homoarginine 156-86-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

Career Henan Chemical Co

Product: Homoarginine 156-86-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-16

156-86-5, HomoarginineRelated Search:

ARGINASE L(+)-Arginine L-HOMOCITRULLINE (S)-4-ACETOXY-2-AMINO-BUTYRIC ACID H-HOMOPRO-OME HCL H-HomoPhe-OtBu.HCl (αS)-α-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride L-BETA-HOMOLEUCINE HYDROCHLORIDE H-HomoArg(Boc)2-OH arginine aspirin L(+)-Homoarginine hydrochloride BOC-N-OMEGA-(NITRO)-L-HOMOARGININE,BOC-HOMOARGININE(NO2)-OH,Boc-N-Nitro-L-HomoArginine D-Homoarginine hydrochloride BOC-HOMOARGININE HCL,BOC-L-HOMOARGININE BOC-L-BETA-HOMOARGININE(TOS) FMOC-HOMOARGININE(PMC)-OH,FMOC-N-OMEGA-(2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL)-L-HOMOARGININE 6-GUANIDINOHEXANOIC ACID FMOC-L-HOMOARGININE, HYDROCHLORIDE SALT

l-lysin

l-n(sup6)-amidinolysine

n(sup6)-(aminoiminomethyl)-l-lysin

L-HOMOARGININE

L-ALPHA-AMINO-EPSILON-GUANIDINOHEXANOIC ACID

H-HOMOARG-OH

H-HOARG-OH

H-HAR-OH

HOMOARGININE

(2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid

Homo-L-arginine

H-HOMOARGININE

L-LYSINE, N6-(AMINOIMINOMETHYL)-

(S)-2-AMINO-6-GUANIDINOHEXANOIC ACID

L-α-Amino-ε-guanidinohexanoic acid

N6-Amidino-L-lysine

C01924

H-HoMoarg-OH(H-HoMoarginine)

L-a-AMino-e-guanidinohexanoic acid

L-Homoarginine≥ 99% (Assay)

L-HomoArg-OH

1-(1,1,2,2-tetrafluoroethoxy)-4-[2-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]propan-2-yl]benzene

Homoarginine USP/EP/BP

Homoarginine,97%

L-Homo-Arginine-OH

Homoarginine reference substance

(3&#x3B2

)-olean-12-ene-3,28-diol

Valine Impurity 28

156-86-5

Unusual Amino Acids

Amino Acids

Chiral Compound