L(+)-Homoarginine hydrochloride
- Product Name
- L(+)-Homoarginine hydrochloride
- CAS No.
- 1483-01-8
- Chemical Name
- L(+)-Homoarginine hydrochloride
- Synonyms
- NSC 145416;HomoArg.HCl;H-HAR-OH HCL;-(+)-Homoarg;L-Homoarg.hcl;H-HArg-OH·HCl;inine hydrochL;H-L-HArg-OH*HCl;H-HOMOARG-OH HCL;H-L-HOARG-OH HCL
- CBNumber
- CB8732118
- Molecular Formula
- C7H17ClN4O2
- Formula Weight
- 224.69
- MOL File
- 1483-01-8.mol
L(+)-Homoarginine hydrochloride Property
- Melting point:
- 213-215 °C(lit.)
- alpha
- 18 º (c=1, 1N HCl)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 50 mg/mL, clear to slightly hazy, faintly yellow
- form
- Granular Powder
- color
- White
- Water Solubility
- Soluble in water(50 mg/mL).
- BRN
- 4016621
- Stability:
- Moisture Sensitive
- CAS DataBase Reference
- 1483-01-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36/37/39-27-26
- WGK Germany
- 3
- HS Code
- 29252900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1007
- Product name
- L-Homoarginine hydrochloride
- Purity
- unnatural arginine analog
- Packaging
- 5g
- Price
- $350
- Updated
- 2024/03/01
- Product number
- H1172
- Product name
- L-Homoarginine Hydrochloride
- Purity
- >97.0%(T)
- Packaging
- 1g
- Price
- $64
- Updated
- 2024/03/01
- Product number
- H1172
- Product name
- L-Homoarginine Hydrochloride
- Purity
- >97.0%(T)
- Packaging
- 5g
- Price
- $188
- Updated
- 2024/03/01
- Product number
- H27387
- Product name
- L-Homoarginine hydrochloride, 98+%
- Packaging
- 1g
- Price
- $65.65
- Updated
- 2024/03/01
- Product number
- H27387
- Product name
- L-Homoarginine hydrochloride, 98+%
- Packaging
- 5g
- Price
- $255
- Updated
- 2024/03/01
L(+)-Homoarginine hydrochloride Chemical Properties,Usage,Production
Description
L-Homoarginine is an uncompetitive and organ-specific inhibitor of alkaline phosphatases. This non-essential amino acid inhibits human bone and liver alkaline phosphatases but has no effect on placental or intestinal isoenzymes. In vitro, L-homoarginine inhibits [3H]thymidine uptake by mouse myeloma MOPC 104E cells and inhibits proliferation of C3H/He mouse osteosarcoma cells. Pre-treatment with L-homoarginine delays in vivo tumor growth in a murine C3H/He osteosarcoma model. It also inhibits high-protein diet-induced pancreatic growth and enzyme secretion in bile-pancreatic juice-diverted rats, a model for the induction of pancreatic enzyme secretion with hypercholecystokininemia.
Chemical Properties
White Powder
Uses
An inhibitor of alkaline phosphatase isoenzymes. An analog of Homoarginine (H585000).
Uses
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
Biochem/physiol Actions
Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
L(+)-Homoarginine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
L(+)-Homoarginine hydrochloride Suppliers
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View Lastest Price from L(+)-Homoarginine hydrochloride manufacturers
- Product
- L-Homoarg.hcl 1483-01-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-25
- Product
- L(+)-Homoarginine hydrochloride 1483-01-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- L-Homoarginine Hydrochloride 1483-01-8
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 50g
- Purity
- 98.0%-101.5%
- Supply Ability
- 100kg
- Release date
- 2021-06-02