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CYCLOPROPANECARBOXAMIDE

Product Name
CYCLOPROPANECARBOXAMIDE
CAS No.
6228-73-5
Chemical Name
CYCLOPROPANECARBOXAMIDE
Synonyms
Win;Arcado;Zabara);Seed One;Win Admir;CPC-Amide;QR 711-d10;CARBOXYAMIDE;Bisguadine-d10;Sterwin 904-d10
CBNumber
CB5299861
Molecular Formula
C4H7NO
Formula Weight
85.1
MOL File
6228-73-5.mol
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CYCLOPROPANECARBOXAMIDE Property

Melting point:
120-122°C
Boiling point:
248.5±7.0 °C(Predicted)
Density 
1.187±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
16.60±0.20(Predicted)
color 
White to Yellow to Orange
Water Solubility 
Insoluble in water.
BRN 
1924346
InChI
InChI=1S/C4H7NO/c5-4(6)3-1-2-3/h3H,1-2H2,(H2,5,6)
InChIKey
AIMMVWOEOZMVMS-UHFFFAOYSA-N
SMILES
C1(C(N)=O)CC1
CAS DataBase Reference
6228-73-5(CAS DataBase Reference)
EPA Substance Registry System
Cyclopropanecarboxamide (6228-73-5)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S455989
Product name
CYCLOPROPANECARBOXAMIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S455989
Product name
CYCLOPROPANECARBOXAMIDE
Purity
Aldrich
Packaging
250mg
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
C2010
Product name
Cyclopropanecarboxamide
Purity
>98.0%(GC)
Packaging
25g
Price
$62
Updated
2025/07/31
TCI Chemical
Product number
C2010
Product name
Cyclopropanecarboxamide
Purity
>98.0%(GC)
Packaging
250g
Price
$365
Updated
2025/07/31
TRC
Product number
C987150
Product name
Cyclopropanecarboxam​ide
Packaging
1g
Price
$55
Updated
2021/12/16
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CYCLOPROPANECARBOXAMIDE Chemical Properties,Usage,Production

Uses

Cyclopropanecarboxamide is used in the preparation of 2-(cyclopropanecarbonyl-amino)-but-2-enoic acid by reacting with 2-oxo-butyric acid.

Definition

ChEBI: Cyclopropanecarboxamide is a cyclopropylcarboxamide.

Reactions

Cyclopropanecarboxamide is an organic intermediate which, for example after conversion to cyclopropylamine, is reacted to give active compounds in the pharmaceutical and plant protection sector.

Synthesis

4023-34-1

6228-73-5

General procedure: synthesis of intermediate 3: cyclopropane carboxamide Ammonia was passed into a well-stirred solution of cyclopropanecarbonyl chloride (1 g, 9.61 mmol) in dichloromethane (10 mL) at room temperature and purged continuously for 2 hours. Upon completion of the reaction, the solvent was removed by vacuum distillation. The residue was dissolved in ethyl acetate and filtered to remove insoluble matter. Subsequently, the filtrate was concentrated to give pure cyclopropanecarboxamide as a crystalline solid (0.81 g, 100% yield). 1H NMR (400 MHz, CHCl3-d): δ 5.63-5.91 (broad single peak, 2H, NH2), 1.43 (multiple peaks, 1H, cyclopropane-CH), 0.98 (double peaks, J = 4.42,2.98 Hz, 2H, cyclopropane-CH2), 0.79 (double peaks, J = 7.91,2.95 Hz, 2H, cyclopropane- CH2). MS (mass spectrum): 85.91 (M + 1).

References

[1] Patent: WO2012/160464, 2012, A1. Location in patent: Page/Page column 59-60
[2] Patent: US2014/155398, 2014, A1. Location in patent: Paragraph 0365
[3] Chemische Berichte, 1923, vol. 56, p. 2201
[4] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1901, vol. 33, p. 377
[5] Chem. Zentralbl., 1901, vol. 72, # II, p. 579

CYCLOPROPANECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLOPROPANECARBOXAMIDE Suppliers

Tianjin YongSheng Biotechnology Co., Ltd.
Tel
022-60987737 13512258274
Fax
86-022-23500597
Email
sales@immortalbio.com
Country
China
ProdList
154
Advantage
55
New Energy Chemicals
Tel
0515-82159099 13770142076
Fax
86-0515-8215909
Email
info@njuchem.com
Country
China
ProdList
242
Advantage
65
Weifang QianJin Fine Chemical Co., Ltd.
Tel
18753684562
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1735
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
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View Lastest Price from CYCLOPROPANECARBOXAMIDE manufacturers

Shandong Vital Biotechnology Co., Ltd.
Product
CYCLOPROPANECARBOXAMIDE 6228-73-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100tons
Release date
2025-11-20
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Cyclopropanecarboxamide 6228-73-5
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-07-17
Hebei Chuanghai Biotechnology Co,.LTD
Product
cyclopropanecarboxamide 6228-73-5
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-20

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