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CYCLOPROPANECARBOXAMIDE

Product Name
CYCLOPROPANECARBOXAMIDE
CAS No.
6228-73-5
Chemical Name
CYCLOPROPANECARBOXAMIDE
Synonyms
Win;Arcado;Zabara);Seed One;Win Admir;CPC-Amide;QR 711-d10;CARBOXYAMIDE;Bisguadine-d10;Sterwin 904-d10
CBNumber
CB5299861
Molecular Formula
C4H7NO
Formula Weight
85.1
MOL File
6228-73-5.mol
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CYCLOPROPANECARBOXAMIDE Property

Melting point:
120-122°C
Boiling point:
248.5±7.0 °C(Predicted)
Density 
1.187±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
16.60±0.20(Predicted)
color 
White to Yellow to Orange
Water Solubility 
Insoluble in water.
BRN 
1924346
InChI
InChI=1S/C4H7NO/c5-4(6)3-1-2-3/h3H,1-2H2,(H2,5,6)
InChIKey
AIMMVWOEOZMVMS-UHFFFAOYSA-N
SMILES
C1(C(N)=O)CC1
CAS DataBase Reference
6228-73-5(CAS DataBase Reference)
EPA Substance Registry System
Cyclopropanecarboxamide (6228-73-5)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S455989
Product name
CYCLOPROPANECARBOXAMIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S455989
Product name
CYCLOPROPANECARBOXAMIDE
Purity
Aldrich
Packaging
250mg
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
C2010
Product name
Cyclopropanecarboxamide
Purity
>98.0%(GC)
Packaging
25g
Price
$62
Updated
2025/07/31
TCI Chemical
Product number
C2010
Product name
Cyclopropanecarboxamide
Purity
>98.0%(GC)
Packaging
250g
Price
$365
Updated
2025/07/31
TRC
Product number
C987150
Product name
Cyclopropanecarboxam​ide
Packaging
1g
Price
$55
Updated
2021/12/16
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CYCLOPROPANECARBOXAMIDE Chemical Properties,Usage,Production

Uses

Cyclopropanecarboxamide is used in the preparation of 2-(cyclopropanecarbonyl-amino)-but-2-enoic acid by reacting with 2-oxo-butyric acid.

Definition

ChEBI: Cyclopropanecarboxamide is a cyclopropylcarboxamide.

Reactions

Cyclopropanecarboxamide is an organic intermediate which, for example after conversion to cyclopropylamine, is reacted to give active compounds in the pharmaceutical and plant protection sector.

Synthesis

4023-34-1

6228-73-5

General procedure: synthesis of intermediate 3: cyclopropane carboxamide Ammonia was passed into a well-stirred solution of cyclopropanecarbonyl chloride (1 g, 9.61 mmol) in dichloromethane (10 mL) at room temperature and purged continuously for 2 hours. Upon completion of the reaction, the solvent was removed by vacuum distillation. The residue was dissolved in ethyl acetate and filtered to remove insoluble matter. Subsequently, the filtrate was concentrated to give pure cyclopropanecarboxamide as a crystalline solid (0.81 g, 100% yield). 1H NMR (400 MHz, CHCl3-d): δ 5.63-5.91 (broad single peak, 2H, NH2), 1.43 (multiple peaks, 1H, cyclopropane-CH), 0.98 (double peaks, J = 4.42,2.98 Hz, 2H, cyclopropane-CH2), 0.79 (double peaks, J = 7.91,2.95 Hz, 2H, cyclopropane- CH2). MS (mass spectrum): 85.91 (M + 1).

References

[1] Patent: WO2012/160464, 2012, A1. Location in patent: Page/Page column 59-60
[2] Patent: US2014/155398, 2014, A1. Location in patent: Paragraph 0365
[3] Chemische Berichte, 1923, vol. 56, p. 2201
[4] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1901, vol. 33, p. 377
[5] Chem. Zentralbl., 1901, vol. 72, # II, p. 579

CYCLOPROPANECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CYCLOPROPANECARBOXAMIDE manufacturers

Shandong Vital Biotechnology Co., Ltd.
Product
CYCLOPROPANECARBOXAMIDE 6228-73-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100tons
Release date
2025-11-20
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Cyclopropanecarboxamide 6228-73-5
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-07-17
Hebei Chuanghai Biotechnology Co,.LTD
Product
cyclopropanecarboxamide 6228-73-5
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-20

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