N-Cbz-1,2-diaMinoethane
- Product Name
- N-Cbz-1,2-diaMinoethane
- CAS No.
- 72080-83-2
- Chemical Name
- N-Cbz-1,2-diaMinoethane
- Synonyms
- benzyl 2-aminoethylcarbamate;(2-AMino-ethyl)-carbaMic acid benzyl ester;Z-EDA HCL;Z-NH(CH2)2NH2 HCL;TIMTEC-BB SBB003280;Z-DIAMINOETHANE HCL;N-Cbz-ethylenediamine;Z-1,2-DIAMINOETHANE HCL;N-CBZ-1,2-DIAMINOETHANE;N1-Cbz-1,2-ethanediamine
- CBNumber
- CB5302152
- Molecular Formula
- C10H14N2O2
- Formula Weight
- 194.23
- MOL File
- 72080-83-2.mol
N-Cbz-1,2-diaMinoethane Property
- Melting point:
- 169-172 °C(lit.)
- Boiling point:
- 188 °C(Press: 4.5 Torr)
- Density
- 1.134±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- pka
- 12.19±0.46(Predicted)
- Appearance
- Colorless to light pink Liquid
- InChI
- InChI=1S/C10H14N2O2/c11-6-7-12-10(13)14-8-9-4-2-1-3-5-9/h1-5H,6-8,11H2,(H,12,13)
- InChIKey
- QMMFTRJQCCVPCE-UHFFFAOYSA-N
- SMILES
- C(OCC1=CC=CC=C1)(=O)NCCN
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B6489
- Product name
- Benzyl (2-Aminoethyl)carbamate
- Packaging
- 1G
- Price
- $66
- Updated
- 2025/07/31
- Product number
- B6489
- Product name
- Benzyl (2-Aminoethyl)carbamate
- Packaging
- 5G
- Price
- $198
- Updated
- 2025/07/31
- Product number
- B130155
- Product name
- Benzyl2-Aminoethylcarbamate
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- Y9906
- Product name
- Benzyl2-aminoethylcarbamate
- Packaging
- 1g
- Price
- $112
- Updated
- 2021/12/16
- Product number
- CS-W005160
- Product name
- Benzyl(2-aminoethyl)carbamate
- Purity
- 96.80%
- Packaging
- 5g
- Price
- $114
- Updated
- 2021/12/16
N-Cbz-1,2-diaMinoethane Chemical Properties,Usage,Production
Synthesis
501-53-1
107-15-3
72080-83-2
Dichloromethane (100 mL), ethylenediamine (39 mL, 0.58 mol) and potassium carbonate (32.4 g, 0.23 mol) were added to a 500 mL three-necked flask under nitrogen protection. The temperature of the reaction system was controlled at -5 to 0°C and a solution of benzyl chloroformate (20.0 g, 0.12 mol) in dichloromethane (100 mL) was slowly added dropwise under stirring. The dropwise addition process was completed in about 1 hour, followed by continued stirring of the reaction for 2 hours at room temperature. Upon completion of the reaction, the reaction mixture was washed with water (200 mL x 2). The organic layer was separated and dried over anhydrous sodium sulfate (10 g). The organic layer was concentrated under reduced pressure to give a light yellow foamy product of 23.4 g. To the residue, ethyl acetate (80 mL) was added and stirred at room temperature until completely dissolved, then petroleum ether (80 mL) was added dropwise to precipitate a white solid (N-Cbz-1,2-diaminoethane). The solid was collected by filtration, and the mother liquor was concentrated to obtain 15.1 g of light yellow oil, the total yield was 66.5%.
References
[1] Chemical Communications, 2017, vol. 53, # 52, p. 7088 - 7091
[2] New Journal of Chemistry, 2013, vol. 37, # 7, p. 1895 - 1905
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 5, p. 550 - 555
[4] Chemistry - A European Journal, 2011, vol. 17, # 19, p. 5251 - 5255
[5] Synthesis, 1984, # 12, p. 1032 - 1033
N-Cbz-1,2-diaMinoethane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Cbz-1,2-diaMinoethane manufacturers
- Product
- N-Cbz-1,2-diaMinoethane 72080-83-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-07
- Product
- BENZYL N-(2-AMINOETHYL)CARBAMATE HYDROCHLORIDE 72080-83-2
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08