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Axitinib Sulfonyl

Product Name
Axitinib Sulfonyl
CAS No.
1348536-59-3
Chemical Name
Axitinib Sulfonyl
Synonyms
Axitinib D;Axitinib Sulfone;Axitinib Impurity b;Axitinib Sulfone Impurity;Axitinib Sulfonyl Impurity;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-;(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfonyl)benzamide (Axitinib Impurity);Axitinib Impurity 6/Axitinib Sulfone/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-benzamide
CBNumber
CB53038984
Molecular Formula
C22H18N4O3S
Formula Weight
418.47
MOL File
1348536-59-3.mol
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Axitinib Sulfonyl Property

Boiling point:
735.3±60.0 °C(Predicted)
Density 
1.393±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.59±0.40(Predicted)
color 
Off-White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M330455
Product name
N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide
Packaging
25mg
Price
$890
Updated
2021/12/16
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Axitinib Sulfonyl Chemical Properties,Usage,Production

Uses

N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide (Axitinib sulfone) is an impurity of axitinib (A794650), a tyrosine kinase inhibitor and is used in cancer therapy.

Axitinib Sulfonyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Axitinib Sulfonyl Suppliers

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1348536-59-3, Axitinib SulfonylRelated Search:

Axitinib Axitinib Impurity 4 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide Axitinib Impurity 27 Axitinib Impurity a BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- α-Descyclohexyl-α-phenyl Oxybutynin Axitinib Impurity 23 Axitinib Impurity 3 Axitinib Impurity 26 Axitinib Impurity 10 Axitinib Impurity d Axitinib Impurity 20 Axitinib Impurity 18 Axitinib Impurity 13 Axitinib Impurity 3 Axitinib Impurity 14 Axitinib Impurity 19

  • Axitinib Impurity b
  • Axitinib Sulfone
  • Axitinib Impurity 6/Axitinib Sulfone/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-benzamide
  • N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide
  • Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-
  • Axitinib D
  • Axitinib Sulfonyl Impurity
  • Axitinib Sulfone Impurity
  • (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfonyl)benzamide (Axitinib Impurity)
  • 1348536-59-3