PDE1-IN-1 (phosphate)
- Product Name
- PDE1-IN-1 (phosphate)
- CAS No.
- 1642303-38-5
- Chemical Name
- PDE1-IN-1 (phosphate)
- Synonyms
- ITI214;ITI-214 phosphate;PDE1-IN-1 (phosphate);Lenrispodun phosphate;ITI-214 phosphate salt;ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.;selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active;(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate
- CBNumber
- CB53041443
- Molecular Formula
- C29H29FN7O5P
- Formula Weight
- 605.57
- MOL File
- 1642303-38-5.mol
PDE1-IN-1 (phosphate) Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:30.0(Max Conc. mg/mL);49.54(Max Conc. mM)
- form
- A solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 30376
- Product name
- ITI214
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 30376
- Product name
- ITI214
- Packaging
- 10mg
- Price
- $632
- Updated
- 2024/03/01
- Product number
- 30376
- Product name
- ITI214
- Packaging
- 5mg
- Price
- $356
- Updated
- 2024/03/01
- Product number
- CS-3627
- Product name
- ITI-214
- Purity
- 99.57%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 3885DW
- Product name
- (11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoricacid
- Packaging
- 10mg
- Price
- $802
- Updated
- 2021/12/16
PDE1-IN-1 (phosphate) Chemical Properties,Usage,Production
Description
ITI214 is an inhibitor of phosphodiesterase 1 (PDE1; Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 μM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when administered at a dose of 50 mg/kg. ITI214 (0.1, 3, and 10 mg/kg) reverses MK-801-induced decreases in spontaneous alteration in the T-maze continuous alternation task in mice.
PDE1-IN-1 (phosphate) Preparation Products And Raw materials
Raw materials
Preparation Products
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