ChemicalBook > CAS DataBase List > 5-FLUORO-2-METHYLBENZIMIDAZOLE

5-FLUORO-2-METHYLBENZIMIDAZOLE

Product Name
5-FLUORO-2-METHYLBENZIMIDAZOLE
CAS No.
118469-15-1
Chemical Name
5-FLUORO-2-METHYLBENZIMIDAZOLE
Synonyms
2-Methyl-5-fluorobenzimidazole;6-Fluoro-2-methylbenzimidazole;5-FLUORO-2-METHYLBENZIMIDAZOLE;5-Fluoro-2-MethylbenziMidiazole;5-FLUORO-2-METHYL-1H-BENZIMIDAZOLE;6-Fluoro-2-methyl-1H-benzimidazole;5-Fluoro-2-methyl-1H-benzoimidazole;1H-BenziMidazole, 6-fluoro-2-Methyl-;5-Fluoro-2-Methyl-1H-benzo[d]iMidazole;1H-Benzimidazole,5-fluoro-2-methyl-(9CI)
CBNumber
CB5306019
Molecular Formula
C8H7FN2
Formula Weight
150.15
MOL File
118469-15-1.mol
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5-FLUORO-2-METHYLBENZIMIDAZOLE Property

Melting point:
177-179℃
Boiling point:
343.6±15.0 °C(Predicted)
Density 
1.299
storage temp. 
Sealed in dry,Room Temperature
pka
10.68±0.10(Predicted)
Appearance
Light brown to brown Solid
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F598155
Product name
5-Fluoro-2-methyl-1H-benzo[d]imidazole
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
Z7916
Product name
5-Fluoro-2-methylbenzimidiazole
Packaging
1g
Price
$111
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0006517
Product name
5-FLUORO-2-METHYLBENZIMIDAZOLE
Purity
95.00%
Packaging
1G
Price
$269.85
Updated
2021/12/16
AK Scientific
Product number
Z7916
Product name
5-Fluoro-2-methylbenzimidiazole
Packaging
10g
Price
$350
Updated
2021/12/16
Chemcia Scientific
Product number
BB20-5368A
Product name
5-Fluoro-2-methyl-1H-benzoimidazole
Purity
95%
Packaging
5G
Price
$435
Updated
2021/12/16
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5-FLUORO-2-METHYLBENZIMIDAZOLE Chemical Properties,Usage,Production

Synthesis

1445-45-0

364-78-3

118469-15-1

GENERAL METHOD: 4-fluoro-2-nitroaniline (1 mmol) was added to a mixture of indium powder (574 mg, 5.0 mmol), acetic acid (0.572 mL, 10 mmol) and ethyl acetate (2 mL). Subsequently, a solution of ethyl acetate (3 mL) of trimethyl orthoacetate (2.0 mmol) was added. The reaction mixture was heated to reflux and stirred under nitrogen protection. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate (30 mL), filtered through diatomaceous earth and the filtrate was poured into 10% NaHCO3 solution (30 mL). The aqueous phase was extracted with ethyl acetate (30 mL x 3), the organic phases were combined and dried with anhydrous MgSO4, filtered and concentrated. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (v/v = 10/90) as eluent to afford 5-fluoro-2-methyl-1H-benzo[d]imidazole. The structures of the products were characterized by 1H NMR, 13C NMR, FTIR and GC-MS and confirmed by comparison with known compounds. For new compounds, HRMS data are also provided.

References

[1] Tetrahedron, 2011, vol. 67, # 41, p. 8027 - 8033

5-FLUORO-2-METHYLBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-2-METHYLBENZIMIDAZOLE Suppliers

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View Lastest Price from 5-FLUORO-2-METHYLBENZIMIDAZOLE manufacturers

Honest Joy Holdings Limited
Product
5-Fluoro-2-methyl-1H-benzo[d]imidazole 118469-15-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98.8%
Supply Ability
100 tons
Release date
2022-01-14

118469-15-1, 5-FLUORO-2-METHYLBENZIMIDAZOLERelated Search:


  • 5-FLUORO-2-METHYLBENZIMIDAZOLE
  • 5-FLUORO-2-METHYL-1H-BENZIMIDAZOLE
  • 1H-Benzimidazole,5-fluoro-2-methyl-(9CI)
  • 6-Fluoro-2-methyl-1H-benzimidazole
  • 5-Fluoro-2-MethylbenziMidiazole
  • 5-Fluoro-2-Methyl-1H-benzo[d]iMidazole
  • 5-Fluoro-2-methyl-1H-benzoimidazole
  • 6-Fluoro-2-methylbenzimidazole
  • 1H-BenziMidazole, 6-fluoro-2-Methyl-
  • 2-Methyl-5-fluorobenzimidazole
  • 118469-15-1
  • 1184-69-1
  • BENZIMIDAZOLE
  • Imidazol&Benzimidazole