Hydroxy-PEG3-PFP ester
- Product Name
- Hydroxy-PEG3-PFP ester
- CAS No.
- 1807537-40-1
- Chemical Name
- Hydroxy-PEG3-PFP ester
- Synonyms
- Hydroxy-PEG3-PFP ester;Hydroxy-PEG3-C2-PFP ester;Perfluorophenyl 3-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)propanoate;2,3,4,5,6-pentafluorophenyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate;Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
- CBNumber
- CB53062512
- Molecular Formula
- C15H17F5O6
- Formula Weight
- 388.28
- MOL File
- 1807537-40-1.mol
Hydroxy-PEG3-PFP ester Property
- Boiling point:
- 440.3±45.0 °C(Predicted)
- Density
- 1.385±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BIPG1444
- Product name
- Hydroxy-PEG3-PFP ester
- Packaging
- 100mg
- Price
- $351
- Updated
- 2021/12/16
Hydroxy-PEG3-PFP ester Chemical Properties,Usage,Production
Uses
Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Hydroxy-PEG3-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hydroxy-PEG3-PFP ester manufacturers
- Product
- Hydroxy-PEG3-C2-PFP ester 1807537-40-1
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-26