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Hydroxy-PEG3-PFP ester

Product Name
Hydroxy-PEG3-PFP ester
CAS No.
1807537-40-1
Chemical Name
Hydroxy-PEG3-PFP ester
Synonyms
Hydroxy-PEG3-PFP ester;Hydroxy-PEG3-C2-PFP ester;Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber
CB53062512
Molecular Formula
C15H17F5O6
Formula Weight
388.28
MOL File
1807537-40-1.mol
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Hydroxy-PEG3-PFP ester Property

Boiling point:
440.3±45.0 °C(Predicted)
Density 
1.385±0.06 g/cm3(Predicted)
pka
14.36±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1444
Product name
Hydroxy-PEG3-PFP ester
Packaging
100mg
Price
$351
Updated
2021/12/16
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Hydroxy-PEG3-PFP ester Chemical Properties,Usage,Production

Biological Activity

Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Hydroxy-PEG3-PFP ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG3-PFP ester Suppliers

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View Lastest Price from Hydroxy-PEG3-PFP ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG3-C2-PFP ester 1807537-40-1
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-26