MAl-PEG6-t-butyl ester

Product Name: MAl-PEG6-t-butyl ester
CAS No.: 518044-37-6
Chemical Name: MAl-PEG6-t-butyl ester
Synonyms: Mal-PEG6-Boc;Mal-PEG6-OtBu;Mal-PEG6-COOtBu;MAL-PEG6-CH2CH2COOTBU;MAl-PEG6-t-butyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;Mal-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
CBNumber: CB53062547
Molecular Formula: C23H39NO10
Formula Weight: 489.56
MOL File: 518044-37-6.mol

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MAl-PEG6-t-butyl ester Property

Boiling point:: 565.2±50.0 °C(Predicted)
Density: 1.149±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
pka: -2.34±0.20(Predicted)
form: Viscous Liquid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-21523
Product name: Mal-PEG6-t-butylester
Purity: 98%
Packaging: 250mg
Price: $360
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1518
Product name: MAl-PEG6-t-butyl ester
Packaging: 250mg
Price: $701
Updated: 2021/12/16

Acrotein

Product number: B-1565
Product name: Mal-PEG6-CH2CH2COOtBu
Purity: 97%
Packaging: 1g
Price: $495
Updated: 2021/12/16

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MAl-PEG6-t-butyl ester Chemical Properties,Usage,Production

Description

Mal-PEG6-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

MAl-PEG6-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MAl-PEG6-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG6-COOtBu 518044-37-6
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

518044-37-6, MAl-PEG6-t-butyl esterRelated Search:

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MAl-PEG6-t-butyl ester

MAL-PEG6-CH2CH2COOTBU

Mal-PEG6-OtBu

Mal-PEG6-COOtBu

Mal-PEG6-Boc

4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester

Mal-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester

tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate

518044-37-6

C23H39NO10

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