(1R,2S,3R)-Aprepitant

Product Name: (1R,2S,3R)-Aprepitant
CAS No.: 1185502-97-9
Chemical Name: (1R,2S,3R)-Aprepitant
Synonyms: (R,S,R)-Aprepitant;Aprepitant impurity;1R, 2S, 3R)-Aripitan;Aprepitant impurity 06;(2S,3R,1’R)-Aprepitant;Aprepitant (R,S,R)-Isomer;Aprepitant impurity 6/(1R,2S,3R)-Aprepitant;5-([(2S,3R)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber: CB53146508
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 1185502-97-9.mol

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(1R,2S,3R)-Aprepitant Property

Density: 1.51±0.1 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A729775
Product name: (2S,3R,1’R)-Aprepitant
Packaging: 1mg
Price: $115
Updated: 2021/12/16

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(1R,2S,3R)-Aprepitant Chemical Properties,Usage,Production

Uses

(2S,3R,1’R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

Definition

ChEBI: 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-1,2,4-triazol-3-one is a member of morpholines.

(1R,2S,3R)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (1R,2S,3R)-Aprepitant manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Aprepitant Impurity 23 1185502-97-9
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-06-11

1185502-97-9, (1R,2S,3R)-AprepitantRelated Search:

Aprepitant Impurity 19 Benzyl dihydrogen phosphate (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Aprepitant Fosaprepitant dimeglumine 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Aprepitant [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Aprepitant Aprepitant 1,1,1-Trimethoxy-2-chloroethane Aprepitant-M3 Metabolite Defluoro Aprepitant Aprepitant Impurity B HCl 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 2 Aprepitant Impurity 11 HCl

(R,S,R)-Aprepitant

Aprepitant (R,S,R)-Isomer

Aprepitant impurity 6/(1R,2S,3R)-Aprepitant

1R, 2S, 3R)-Aripitan

5-([(2S,3R)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one

3H-1,2,4-Triazol-3-one, 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

(2S,3R,1’R)-Aprepitant

Aprepitant impurity 06

Aprepitant impurity

3-(((2S,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one (Aprepitant impurity)

1185502-97-9