ChemicalBook > CAS DataBase List > (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- Product Name
- (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- CAS No.
- 327623-37-0
- Chemical Name
- (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- Synonyms
- Aprepitant Impurity 1;Aprepitant Impurity 11;Fosaprepitant Impurity 30;Aprepitant M2 Metabolite Enantiomer;Aprepitant Impurity 1 Hydrochloride;Aprepitant Impurity 10 Hydrochloride;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1’Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- CBNumber
- CB12657010
- Molecular Formula
- C20H18F7NO2
- Formula Weight
- 437.35
- MOL File
- 327623-37-0.mol
More
Less
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Property
- Boiling point:
- 387.9±42.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- pka
- 6.93±0.60(Predicted)
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- D297830
- Product name
- Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1''S)-Aprepitant
- Packaging
- 1mg
- Price
- $90
- Updated
- 2021/12/16
More
Less
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemical Properties,Usage,Production
Uses
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 14055
- Advantage
- 65
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5050
- Advantage
- 50
- Tel
- Mobile:13665161512
- Fax
- +86-510-68873513
- Country
- China
- ProdList
- 1785
- Advantage
- 58
- Tel
- 0086-571-86217390
- Fax
- 0086-571-86217391
- Sales@gihichem.com
- Country
- China
- ProdList
- 860
- Advantage
- 58
- Tel
- 13148101715
- Fax
- 021-20237859
- 2073632910@qq.com
- Country
- China
- ProdList
- 38
- Advantage
- 55
- Tel
- 021-64609169 18901607656
- Fax
- 021-64609160
- greensnown@163.com
- Country
- China
- ProdList
- 9906
- Advantage
- 50
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 025-66023220 0086-15250997978
- Fax
- 025-58362220
- 1511893459@qq.com
- Country
- China
- ProdList
- 7850
- Advantage
- 55
- Tel
- 025-87787262
- Fax
- 025-87787262
- Country
- China
- ProdList
- 496
- Advantage
- 58
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9923
- Advantage
- 65
327623-37-0, (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)MorpholineRelated Search:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine
Aprepitant
Fosaprepitant dimeglumine
Aprepitant
Aprepitant
Aprepitant
Fosaprepitant Impurity 6
(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE
Aprepitant
Fosaprepitant Impurity 5
5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one
(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
1,1,1-Trimethoxy-2-chloroethane
Aprepitant
Benzyl dihydrogen phosphate