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Anavex 2-73

Product Name
Anavex 2-73
CAS No.
195615-84-0
Chemical Name
Anavex 2-73
Synonyms
CS-2759;Anavex 2-73;AVex-73 HCl;Blarcamesine;Anavex2-73 HCl;AVex-73 hydrochL;AE-37 HYDROCHLORIDE;AN2/AVEX-73 HCL SALT;AVex-73 hydrochloride;Anavex 2-73(ANAVEX2-73)
CBNumber
CB53151652
Molecular Formula
C19H24ClNO
Formula Weight
317.86
MOL File
195615-84-0.mol
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Anavex 2-73 Property

Melting point:
165 - 168°C
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C19H23NO.ClH/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17;/h3-12,18H,13-15H2,1-2H3;1H
InChIKey
FEQOLYDPQKHFTD-UHFFFAOYSA-N
SMILES
C(C1CCOC1(C1C=CC=CC=1)C1C=CC=CC=1)N(C)C.Cl
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A637195
Product name
Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamineHydrochloride(>75%)
Packaging
25mg
Price
$125
Updated
2021/12/16
Usbiological
Product number
254635
Product name
ANAVEX 2-73
Packaging
10mg
Price
$446
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
50mg
Price
$660
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
100mg
Price
$972
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
5mg
Price
$132
Updated
2021/12/16
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Anavex 2-73 Chemical Properties,Usage,Production

Uses

Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine Hydrochloride is a useful therapeutic in the treatment of humans suffering from insomnia, anxiety, or agitation.Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine Hydrochloride is also used in pharmacological studies such as the anti-amnesic and neuroprotective potentials of mixed muscarinic receptor/σ1 ligand ANAVEX2-73 as novel aminotetrahydrofuran deriv.

in vivo

The pre-administration of Blarcamesine leads to a dose-dependent attenuation of the scopolamine induced alternation deficit, significant at 1 and 3 mg/kg. The pre-treatment with Blarcamesine hydrochloride attenuates the impairments of step-through latency, dose dependently and significantly at doses higher than 0.3 mg/kg[1]. The Blarcamesine hydrochloride treatment dose-dependently blocks the recognition memory deficit, with a significant effect measured at 1?mg/kg. One day after injections, the significant Aβ25-35-induced decrease in Akt phosphorylation is significantly attenuated by Blarcamesine hydrochloride at 0.1 and 1?mg/kg dose. Seven days after injections, Blarcamesine hydrochloride attenuates the decrease in Ser9 phosphorylation induced by the peptide at 0.3 and 1?mg/kg. The Blarcamesine hydrochloride treatment dose-dependently prevents the Aβ25-35-induced increase in Aβ1-42 content, with a significant effect at the highest dose tested[2].

IC 50

Sigma 1 Receptor

Anavex 2-73 Preparation Products And Raw materials

Raw materials

Preparation Products

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Anavex 2-73 Suppliers

China 88 United States 8 Global 96
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
7047
Advantage
58
Shenzhen Fulkare Biotechnology Co., Ltd.
Tel
15953196022
Email
fulkare@163.com
Country
China
ProdList
88
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Shanghai URChem Limited
Tel
+86-021-50890968，021-50891159 +86-18601776121
Fax
086-21-68416099 58604179
Email
danny@urchem.com
Country
China
ProdList
628
Advantage
58
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View Lastest Price from Anavex 2-73 manufacturers

Career Henan Chemical Co
Product
Anavex 2-73 195615-84-0
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

195615-84-0, Anavex 2-73Related Search:

Tetrahydro-N-methyl-2,2-diphenyl-3-furanmethanamine hydrochloride salt

  • Anavex 2-73
  • AE-37 HYDROCHLORIDE
  • AN2/AVex-73 hydrochloride salt
  • AN2/AVEX-73 HCL SALT
  • AVex-73 hydrochloride
  • Anavex2-73 HCl
  • CS-2759
  • AE-37; AVEX-73; ANAVEX-2-73; ANAVEX-273; AE37; AVEX73; ANAVEX273; AE 37; AVEX 73; ANAVEX 2 73; ANAVEX 273; BLARCAMESINE
  • Blarcamesine
  • Anavex 2-73(ANAVEX2-73)
  • AVex-73 hydrochloride(AE-37)
  • Blarcamesine hydrochloride
  • AVex-73 hydrochL
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride salt
  • 1-(2,2-Diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride
  • Anavex 2-73 hydrochloride
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride
  • Inhibitor,Blarcamesine,Blarcamesine hydrochloride,inhibit,Sigma Receptor
  • AVex-73 HCl
  • Blarcamesine hydrochloride, 10 mM in DMSO
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride98%
  • 195615-84-0
  • API