D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID

Product Name: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
CAS No.: 4350-07-6
Chemical Name: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
Synonyms: (R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;D-5-HTP;5-hydroxy-d-tryptopha;D-5-HYDROXYTRYPTOPHAN;Tryptophan Impurity 42;D-Tryptophan, 5-hydroxy-;D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid;(2R)-2-azanyl-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
CBNumber: CB5315752
Molecular Formula: C11H12N2O3
Formula Weight: 220.22
MOL File: 4350-07-6.mol

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D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID Property

Melting point:: 270C
Boiling point:: 520.6±50.0 °C(Predicted)
Density: 1.484±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 2.22±0.10(Predicted)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21-20/21/22-36/37/38-65
Safety Statements: 26-36

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS102106
Product name: 5-Hydroxy-D-tryptophan
Purity: 95% ee
Packaging: 1g
Price: $634
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0002076
Product name: D-TRYPTOPHAN, 5-HYDROXY-
Purity: 95.00%
Packaging: 100MG
Price: $696.36
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0002076
Product name: D-TRYPTOPHAN, 5-HYDROXY-
Purity: 95.00%
Packaging: 250MG
Price: $2042.25
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0002076
Product name: D-TRYPTOPHAN, 5-HYDROXY-
Purity: 95.00%
Packaging: 1G
Price: $3825.15
Updated: 2021/12/16

Crysdot

Product number: CD21007194
Product name: (R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacid
Purity: 95+%
Packaging: 250mg
Price: $303
Updated: 2021/12/16

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D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID Chemical Properties,Usage,Production

Uses

D-5-Hydroxytryptophan (D-5-HTP) is the D-isomer of 5-HTP and can be isolated from DL-5-hydroxytryptophan by continuous separation. Compared with intraperitoneal administration of L-5-Hydroxytryptophan, which can induce dose-dependent backward walking behavior in mice, D-5-Hydroxytryptophan has no significant effect on mouse behavior and is a negative control. D-5-Hydroxytryptophan is also a 5-HT ligand, capable of binding to the 5-HT site with affinity in the micromolar range[1][2][3].

Definition

ChEBI: The D-enantiomer of 5-hydroxytryptophan.

in vivo

D-5-Hydroxytryptophan (100, 320 mg/kg; ip; single dose) cannot induce backward walking behavior in mice, while L-5-Hydroxytryptophan can do it^[3].

References

[1] J Arendt, et al. Alternative pathways of 5-hydroxyindole metabolism. II. The role transamination in the metabolism of D-5-hydroxytryptophan in the rat. Biochem Pharmacol. 1967 Mar;16(3):419-22. DOI:10.1016/0006-2952(67)90088-3
[2] Acton G. Effects of D-5-hydroxytryptophan and D-DOPA on binding at serotonin and dopamine receptors. Res Commun Chem Pathol Pharmacol. 1988 Apr;60(1):129-32. PMID:3132733
[3] Shimomura K, et al. Backward walking induced by L-5-hydroxytryptophan in mice. Jpn J Pharmacol. 1981 Feb;31(1):39-46. DOI:10.1254/jjp.31.39

D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID Suppliers

China 10 Germany 1 Switzerland 1 United Kingdom 1 United States 3 Global 16

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
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Shanghai Yihe Biological Technology Co., Ltd.

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Fax: 021-68882955
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Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
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DONBOO AMINO ACID COMPANY

Tel: +8618051385538
Email: donboo@donboo.com
Country: China
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DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
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Jilin Chinese Academy of Sciences-yanshen Technology

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China National Standard Pharmaceutical Corporation Limited

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Shenzhen Shenchuang Biopharmaceutical Co., Ltd.

Tel: 0755-86574859
Country: CHINA
ProdList: 167
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4350-07-6, D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACIDRelated Search:

L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID,L-2-Amino-3-(5-hydroxyindolyl)propionic acid, L-5-HTP 5-Hydroxymethylfurfural Isoimperatorin Soapnut Extract DL-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID,DL-2-Amino-3-(5-hydroxyindolyl)propionic acid, DL-5-HTP 2-(3-INDOLYLMETHYL)-L-TRYPTOPHAN 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione 2-(1H-indol-3-yl)acetaldehyde N-Acetyl-L-tryptophan 2-Hydroxy-DL-tryptophan 3-(phenylamino)alanine HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID Tryptophan Impurity 1（Tryptophan EP Impurity A） DL-METHIONINE SULFOXIDE L-2-hydroxyTryptophan hydrochloride Fmoc-Trp(Boc)-OH 5-(1H-indol-3-ylmethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one Tryptophan Impurity 3

(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid

(2R)-2-azanyl-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID

D-5-HTP

D-5-HYDROXYTRYPTOPHAN

(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

(R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

5-hydroxy-d-tryptopha

D-Tryptophan, 5-hydroxy-

Tryptophan Impurity 42

4350-07-6