CID5721353

Product Name: CID5721353
CAS No.: 301356-95-6
Chemical Name: CID5721353
Synonyms: CID5721353;BCL6 inhibitor;79-6（CID5721353）;CID-5721353;CID 5721353;CID5721353 BDL6 inhribitor;BCL6 inhibitor(CID5721353);CID5721353, BCL6 inhibitor;79-6 (CID5721353， BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
CBNumber: CB53159456
Molecular Formula: C15H9BrN2O6S2
Formula Weight: 457.28
MOL File: 301356-95-6.mol

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CID5721353 Property

Density: 2.06±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 3.02±0.23(Predicted)
color: Light brown to brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 25mg
Price: $190
Updated: 2024/03/01

AK Scientific

Product number: 6486CL
Product name: 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
Packaging: 5mg
Price: $313
Updated: 2021/12/16

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CID5721353 Chemical Properties,Usage,Production

Description

CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; K_i = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI₅₀s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI₅₀ = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.

CID5721353 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID5721353 Suppliers

China 47 United States 6 USA 1 Global 54

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

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View Lastest Price from CID5721353 manufacturers

Career Henan Chemical Co

Product: CID5721353 301356-95-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

301356-95-6, CID5721353Related Search:

CID5721353

CID5721353, BCL6 inhibitor

BCL6 inhibitor(CID5721353)

CID5721353 BDL6 inhribitor

CID-5721353;CID 5721353

79-6 (CID5721353， BCL6 inhibitor)

CID 5721353;CID-5721353;CID 5721353

2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid

BCL6 inhibitor

Butanedioic acid, 2-[5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]-

Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353

79-6（CID5721353）

301356-95-6

C15H9BrN2O6S2

API