CID5721353

Product Name: CID5721353
CAS No.: 301356-95-6
Chemical Name: CID5721353
Synonyms: CID5721353;BCL6 inhibitor;79-6（CID5721353）;CID-5721353;CID 5721353;CID5721353 BDL6 inhribitor;BCL6 inhibitor(CID5721353);CID5721353, BCL6 inhibitor;79-6 (CID5721353， BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
CBNumber: CB53159456
Molecular Formula: C15H9BrN2O6S2
Formula Weight: 457.28
MOL File: 301356-95-6.mol

More

Less

CID5721353 Property

Density: 2.06±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 3.02±0.23(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 22967
Product name: CID-5721353
Packaging: 25mg
Price: $190
Updated: 2024/03/01

AK Scientific

Product number: 6486CL
Product name: 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
Packaging: 5mg
Price: $313
Updated: 2021/12/16

More

Less

CID5721353 Chemical Properties,Usage,Production

Description

CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; K_i = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI₅₀s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI₅₀ = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.

CID5721353 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CID5721353 Suppliers

China 43 United States 5 USA 1 Global 49

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

More

Less

View Lastest Price from CID5721353 manufacturers

Career Henan Chemical Co

Product: CID5721353 301356-95-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

301356-95-6, CID5721353Related Search:

CID5721353

CID5721353, BCL6 inhibitor

BCL6 inhibitor(CID5721353)

CID5721353 BDL6 inhribitor

CID-5721353;CID 5721353

79-6 (CID5721353， BCL6 inhibitor)

CID 5721353;CID-5721353;CID 5721353

2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid

BCL6 inhibitor

Butanedioic acid, 2-[5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]-

Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353

79-6（CID5721353）

301356-95-6

C15H9BrN2O6S2

API