Azide-PEG12-Tos

Product Name: Azide-PEG12-Tos
CAS No.: 1821464-56-5
Chemical Name: Azide-PEG12-Tos
Synonyms: N3-PEG12-Tos;Azide-PEG12-Tos;Azido-PEG12-Tos;Azide PEG12 Tos,AzidePEG12Tos,Inhibitor,Azide-PEG-12-Tos,PROTAC Linkers,inhibit;35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl 4-methylbenzenesulfonate;N3-PEG12-Tos/3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-ol, 35-azido-, 1-(4-methylbenzenesulfonate);2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
CBNumber: CB53162854
Molecular Formula: C31H55N3O14S
Formula Weight: 725.85
MOL File: 1821464-56-5.mol

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Azide-PEG12-Tos Property

solubility: Soluble in DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23149
Product name: Azide-PEG12-Tos
Purity: 98%
Packaging: 250mg
Price: $430
Updated: 2021/12/16

Activate Scientific

Product number: AS107799
Product name: N3-PEG12-Tos
Purity: 97%
Packaging: 1g
Price: $1126
Updated: 2021/12/16

Acrotein

Product number: B-1430
Product name: N3-PEG12-Tos
Purity: 97%
Packaging: 0.25g
Price: $366.67
Updated: 2021/12/16

Acrotein

Product number: B-1430
Product name: N3-PEG12-Tos
Purity: 97%
Packaging: 0.5g
Price: $550
Updated: 2021/12/16

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Azide-PEG12-Tos Chemical Properties,Usage,Production

Description

Azide-PEG12-Tos is a monodisperse PEG reagent containing an azide group and a tosyl group. Long PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic reactions.

Uses

Azide-PEG12-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG12-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azide-PEG12-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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Azide-PEG12-Tos Suppliers

China 29 United States 2 Global 31

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Nextpeptide Inc

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Easy CDMO Co.,Ltd

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shandong fen Boyu Biotechnology Co.,LTD

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Shanghai Yanfen Biochemical Technology Co.,LTD

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Shandong Dongde New Materials Co., Ltd

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Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.

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Sangon Biotech (Shanghai) Co.,Ltd.

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Henan Mengtai Pharmaceutical Technology Co., Ltd

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Aikon International Limited

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Biosynth Biological Technology (Suzhou) Co Ltd

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Xian confluore Biological Technology Co., Ltd.

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Jilin Chinese Academy of Sciences-yanshen Technology

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Absin Bioscience Inc.

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Proteintech China

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View Lastest Price from Azide-PEG12-Tos manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG12-Tos 1821464-56-5
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-23

1821464-56-5, Azide-PEG12-TosRelated Search:

N3-PEG12-N3 Azido-PEG12-Br Azido-PEG12-NHS ester N3-PEG12-OH N3-PEG12-Hydrazide N3-PEG12-CH2CH2COOH Azido-PEG12-NHBoc Azido-PEG12-Amine Azido-PEG12-t-butyl ester

Azide-PEG12-Tos

N3-PEG12-Tos

2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

Azido-PEG12-Tos

Azide PEG12 Tos,AzidePEG12Tos,Inhibitor,Azide-PEG-12-Tos,PROTAC Linkers,inhibit

N3-PEG12-Tos/3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-ol, 35-azido-, 1-(4-methylbenzenesulfonate)

35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl 4-methylbenzenesulfonate

1821464-56-5

C31H55N3O14S