NH-(PEG1-OH)2
- Product Name
- NH-(PEG1-OH)2
- CAS No.
- 54384-47-3
- Chemical Name
- NH-(PEG1-OH)2
- Synonyms
- NH-bis-PEG2;NH-(PEG1-OH)2;NH-bis(PEG1-OH);Ethanol, 2,2'-[iminobis(2,1-ethanediyloxy)]bis-;2-[2-[2-(2-hydroxyethoxy)ethylamino]ethoxy]ethanol;2,2’-[[Azanediylbis(ethane-2,1-diyl)]bis(oxy)]diethanol;2-(2-{[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol
- CBNumber
- CB53163073
- Molecular Formula
- C8H19NO4
- Formula Weight
- 193.24
- MOL File
- 54384-47-3.mol
NH-(PEG1-OH)2 Property
- Boiling point:
- 128 °C(Press: 0.02 Torr)
- Density
- 1.090±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 14.09±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- BP-23224
- Product name
- NH-bis(PEG1-OH)
- Purity
- 98%
- Packaging
- 250mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- BP-23224
- Product name
- NH-bis(PEG1-OH)
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-23224
- Product name
- NH-bis(PEG1-OH)
- Purity
- 98%
- Packaging
- 1g
- Price
- $780
- Updated
- 2021/12/16
- Product number
- 3741CT
- Product name
- 2,2'-((Azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol
- Packaging
- 500mg
- Price
- $896
- Updated
- 2021/12/16
- Product number
- 3741CT
- Product name
- 2,2'-((Azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol
- Packaging
- 1g
- Price
- $1121
- Updated
- 2021/12/16
NH-(PEG1-OH)2 Chemical Properties,Usage,Production
Description
NH-bis(PEG1-OH) can be used to conjugate with carboxylic acid in the presence of HATU or EDC
Biological Activity
NH-bis(PEG1-OH) is a non-cleavable 2-unit PEG ADC linker for the synthesis of antibody drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| Non-cleavable < span> | PEGs
|
NH-(PEG1-OH)2 Preparation Products And Raw materials
Raw materials
Preparation Products
NH-(PEG1-OH)2 Suppliers
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
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- United States
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- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
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- Tel
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- Fax
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- sales@medchemexpress.com
- Country
- United States
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View Lastest Price from NH-(PEG1-OH)2 manufacturers
- Product
- NH-bis(PEG1-OH) 54384-47-3
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >95.00%
- Supply Ability
- 10g
- Release date
- 2024-03-28