ChemicalBook > CAS DataBase List > 9-(BETA-D-ARABINOFURANOSYL)GUANINE

9-(BETA-D-ARABINOFURANOSYL)GUANINE

Product Name
9-(BETA-D-ARABINOFURANOSYL)GUANINE
CAS No.
38819-10-2
Chemical Name
9-(BETA-D-ARABINOFURANOSYL)GUANINE
Synonyms
Ara-G;Ara-Gr;Ara-rG;9-βNsc 76352;Ara G,AraG;Araguanosine;ara-Guanosine;Ara-G hydrate;arabinoguansine
CBNumber
CB5316537
Molecular Formula
C10H13N5O5
Formula Weight
283.24
MOL File
38819-10-2.mol
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9-(BETA-D-ARABINOFURANOSYL)GUANINE Property

Melting point:
225°C(lit.)
Density 
2.25±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO: >10mg/mL
pka
9?+-.0.20(Predicted)
form 
solid
color 
White to Off-White
λmax
252nm(lit.)
InChIKey
NYHBQMYGNKIUIF-FJFJXFQQSA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
MF8301000
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A4233
Product name
Ara-G hydrate
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$146
Updated
2024/03/01
Sigma-Aldrich
Product number
A4233
Product name
Ara-G hydrate
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$557
Updated
2024/03/01
TCI Chemical
Product number
A2739
Product name
9-beta-D-Arabinofuranosylguanine Hydrate
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$55
Updated
2024/03/01
TCI Chemical
Product number
A2739
Product name
9-beta-D-Arabinofuranosylguanine Hydrate
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
27984
Product name
Ara-G
Packaging
100mg
Price
$61
Updated
2024/03/01
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9-(BETA-D-ARABINOFURANOSYL)GUANINE Chemical Properties,Usage,Production

Description

Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine . Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA. Ara-G inhibits DNA replication by 92% after 30 minutes when used at a concentration of 50 μM in CEM cells, which are used as a model for human T lymphoblasts. It also halts the cell cycle at the sub-G1 phase and induces apoptosis in CEM cells. Syngeneic bone marrow containing 6C3HED tumor cells treated with ara-G (100 mM) ex vivo prior to transplantation increases survival of lethally irradiated mice and induces reconstitution of lymphoid, myeloid, and erythroid cell linages.

Uses

Ara-G is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.

Definition

ChEBI: A purine nucleoside in which guanine is attached to arabinofuranose via a beta-N9-glycosidic bond. It inhibits DNA synthesis and causes cell death.

9-(BETA-D-ARABINOFURANOSYL)GUANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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9-(BETA-D-ARABINOFURANOSYL)GUANINE Suppliers

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View Lastest Price from 9-(BETA-D-ARABINOFURANOSYL)GUANINE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
9-beta-D-Arabinofuranosylguanine Hydrate 38819-10-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-10-13
Zhuozhou Wenxi import and Export Co., Ltd
Product
Arabinoguanosine 38819-10-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Arabinoguanosine 38819-10-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

38819-10-2, 9-(BETA-D-ARABINOFURANOSYL)GUANINERelated Search:

NADP sodium salt GUANINE-BETA-D-ARABINOFURANOSIDE, [8-3H]- 9-(2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)-GUANINE HYPOXANTHINE-9-BETA-D-ARABINOFURANOSIDE 9-(BETA-D-ARABINOFURANOSYL)GUANINE

  • 9-beta-D-Arabinofuranosylguanine Hydrate
  • 2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
  • Arabinoguanosine
  • Araguanosine
  • ara-Guanosine
  • Guanine arabinoside
  • 9-β-D-Arabinofuranosyl guanine hydrate
  • 9-beta-Arabinosylguanine
  • 6H-Purin-6-one,2-amino-9-b-D-arabinofuranosyl-1,9-dihydro-
  • 2-amino-9-(beta-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one
  • Ara-G hydrate, 98%, inhibitor of DNA synthesis, an antimetabolite and antineoplastic.
  • )-9-Bromo-8,9,10,11-tetrahydrobenz[a]anthracene-8,10,11-triol-d9
  • )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
  • )-9,11-Epoxy-pregna-1,4,16-triene-3,20-dione
  • )-9,11-Epoxy-1,21-dihydroxy-4,16-dimethyl-19-norpregna-1,3,5(10)-trien-20-one
  • -Epoxy-21dehydroxy Betamethasone
  • )-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
  • )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-16-methyl-d3-pregna-1,4-diene-3,20-dione
  • 9-&beta
  • 2-amino-9-beta-d-arabinofuranosyl-1,9-dihydro-6h-purin-6-on
  • 9-(beta-d-arabinofuranosyl)-guanin
  • 9-(BETA-D-ARABINOFURANOSYL)GUANINE
  • GUANINE-9-ARABINOSIDE
  • ARABINOFURANOSYL-GUANINE
  • 9-(b-D-Arabinofuranosyl)guanine
  • 9-arabinofuranosylguanine
  • ARA-G 9-(BETA-D-ARABINOFURANOSYL)-GUANINE
  • 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one
  • 2-Amino-9-β-D-arabinofuranosyl-9H-purine-6(1H)-one
  • 9-β-D-Arabinofuranosyl-1,6-dihydro-2-amino-6-oxo-9H-purine
  • 9-β-D-Arabinofuranosyl-2-amino-9H-purin-6-ol
  • Arabinosylguanine
  • Ara-G
  • Ara-G hydrate
  • 9-(β-D-Arabinoribofuranosyl)-guanine
  • 6H-Purin-6-one, 2-amino-9-beta-D-arabinofuranosyl-1,9-dihydro-
  • Guanine, 9-(beta-D-arabinofuranosyl)-
  • Nsc 76352
  • 9-(β-D-Arabinofuranosyl)guanine ,97%
  • -<small>D</small>-Arabinofuranosylguanine Hydrate
  • -methyl-pregn-4-ene-3,20-dione
  • )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-pregna-1,4,16-triene-3,20-dione
  • -Epoxy-17,21-dihydroxy-16&beta
  • )-10-Bromo-8,9,10,11-tetrahydrobenz[a]anthracene-8,9,11-triol
  • )-21-(Acetyloxy)-9,11-epoxypregna-1,4,16-triene-3,20-dione
  • )-9,11-Epoxy-6-fluoro-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
  • )-9,11-Epoxy-6-fluoropregna-1,4,16-triene-3,20-dione
  • 1-β-D-Arabinofuranosylguanine
  • Ara-Gr
  • 9-β-D-Arabinofuranosylguanine Hydrate &gt
  • 6H-Purin-6-one, 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-
  • 9-β-D-Arabinofuranosylguanine
  • Arabinofuranosyl-guanine (ara-G)
  • 9-(BETA-D-ARABINOFURANOSYL)GUANINE USP/EP/BP
  • 9-β-D-Arabinofuranosylguanine Hydrate
  • 2-amino-9-(beta-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-o...
  • Ara G,AraG
  • 6H-Purin-6-one, 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-