9-(BETA-D-ARABINOFURANOSYL)GUANINE
- Product Name
- 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- CAS No.
- 38819-10-2
- Chemical Name
- 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- Synonyms
- Ara-G;Ara-Gr;Ara-rG;9-βNsc 76352;Ara G,AraG;Araguanosine;ara-Guanosine;Ara-G hydrate;arabinoguansine
- CBNumber
- CB5316537
- Molecular Formula
- C10H13N5O5
- Formula Weight
- 283.24
- MOL File
- 38819-10-2.mol
9-(BETA-D-ARABINOFURANOSYL)GUANINE Property
- Melting point:
- 225°C(lit.)
- Density
- 2.25±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO: >10mg/mL
- pka
- 9?+-.0.20(Predicted)
- form
- solid
- color
- White to Off-White
- λmax
- 252nm(lit.)
- InChIKey
- NYHBQMYGNKIUIF-FJFJXFQQSA-N
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- MF8301000
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A4233
- Product name
- Ara-G hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $146
- Updated
- 2024/03/01
- Product number
- A4233
- Product name
- Ara-G hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $557
- Updated
- 2024/03/01
- Product number
- A2739
- Product name
- 9-beta-D-Arabinofuranosylguanine Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 10mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- A2739
- Product name
- 9-beta-D-Arabinofuranosylguanine Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 50mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 27984
- Product name
- Ara-G
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
9-(BETA-D-ARABINOFURANOSYL)GUANINE Chemical Properties,Usage,Production
Description
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine . Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA. Ara-G inhibits DNA replication by 92% after 30 minutes when used at a concentration of 50 μM in CEM cells, which are used as a model for human T lymphoblasts. It also halts the cell cycle at the sub-G1 phase and induces apoptosis in CEM cells. Syngeneic bone marrow containing 6C3HED tumor cells treated with ara-G (100 mM) ex vivo prior to transplantation increases survival of lethally irradiated mice and induces reconstitution of lymphoid, myeloid, and erythroid cell linages.
Uses
Ara-G is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.
Definition
ChEBI: A purine nucleoside in which guanine is attached to arabinofuranose via a beta-N9-glycosidic bond. It inhibits DNA synthesis and causes cell death.
9-(BETA-D-ARABINOFURANOSYL)GUANINE Preparation Products And Raw materials
Raw materials
Preparation Products
9-(BETA-D-ARABINOFURANOSYL)GUANINE Suppliers
- Tel
- 25-25-58740604 15951658055
- Fax
- +86-25-58356858
- sales@unisyn.cn
- Country
- China
- ProdList
- 561
- Advantage
- 58
- Tel
- 15737397775
- 970007865@qq.com
- Country
- China
- ProdList
- 16
- Advantage
- 58
- Tel
- 153-0048-7802 15300487802
- jlin@microbiosyn.com
- Country
- China
- ProdList
- 164
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-64757213
- Fax
- 86-21-64700613
- info@hongene.com
- Country
- China
- ProdList
- 672
- Advantage
- 61
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-51613915-820 13611835272
- Fax
- 021 51613951
- mmwang@sunwaypharm.cn
- Country
- China
- ProdList
- 9734
- Advantage
- 57
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 9-(BETA-D-ARABINOFURANOSYL)GUANINE manufacturers
- Product
- 9-beta-D-Arabinofuranosylguanine Hydrate 38819-10-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98.0%
- Supply Ability
- 1kg/month
- Release date
- 2021-10-13
- Product
- Arabinoguanosine 38819-10-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Arabinoguanosine 38819-10-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08