ChemicalBook > CAS DataBase List > 9-(BETA-D-ARABINOFURANOSYL)GUANINE
9-(BETA-D-ARABINOFURANOSYL)GUANINE
- Product Name
- 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- CAS No.
- 38819-10-2
- Chemical Name
- 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- Synonyms
- Ara-G;Ara-Gr;Ara-rG;9-βNsc 76352;Ara G,AraG;Araguanosine;ara-Guanosine;Ara-G hydrate;arabinoguansine
- CBNumber
- CB5316537
- Molecular Formula
- C10H13N5O5
- Formula Weight
- 283.24
- MOL File
- 38819-10-2.mol
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9-(BETA-D-ARABINOFURANOSYL)GUANINE Property
- Melting point:
- 225°C(lit.)
- Density
- 2.25±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO: >10mg/mL
- pka
- 9?+-.0.20(Predicted)
- form
- solid
- color
- White to Off-White
- λmax
- 252nm(lit.)
- InChIKey
- NYHBQMYGNKIUIF-FJFJXFQQSA-N
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Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- MF8301000
- HS Code
- 29349990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A4233
- Product name
- Ara-G hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $146
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A4233
- Product name
- Ara-G hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $557
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A2739
- Product name
- 9-beta-D-Arabinofuranosylguanine Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 10mg
- Price
- $55
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A2739
- Product name
- 9-beta-D-Arabinofuranosylguanine Hydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 50mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27984
- Product name
- Ara-G
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
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9-(BETA-D-ARABINOFURANOSYL)GUANINE Chemical Properties,Usage,Production
Description
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine . Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA. Ara-G inhibits DNA replication by 92% after 30 minutes when used at a concentration of 50 μM in CEM cells, which are used as a model for human T lymphoblasts. It also halts the cell cycle at the sub-G1 phase and induces apoptosis in CEM cells. Syngeneic bone marrow containing 6C3HED tumor cells treated with ara-G (100 mM) ex vivo prior to transplantation increases survival of lethally irradiated mice and induces reconstitution of lymphoid, myeloid, and erythroid cell linages.
Uses
Ara-G is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.
Definition
ChEBI: A purine nucleoside in which guanine is attached to arabinofuranose via a beta-N9-glycosidic bond. It inhibits DNA synthesis and causes cell death.
9-(BETA-D-ARABINOFURANOSYL)GUANINE Preparation Products And Raw materials
Raw materials
Preparation Products
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9-(BETA-D-ARABINOFURANOSYL)GUANINE Suppliers
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View Lastest Price from 9-(BETA-D-ARABINOFURANOSYL)GUANINE manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 9-beta-D-Arabinofuranosylguanine Hydrate 38819-10-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98.0%
- Supply Ability
- 1kg/month
- Release date
- 2021-10-13
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Arabinoguanosine 38819-10-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Arabinoguanosine 38819-10-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
38819-10-2, 9-(BETA-D-ARABINOFURANOSYL)GUANINERelated Search:
NADP sodium salt
GUANINE-BETA-D-ARABINOFURANOSIDE, [8-3H]-
9-(2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)-GUANINE
HYPOXANTHINE-9-BETA-D-ARABINOFURANOSIDE
9-(BETA-D-ARABINOFURANOSYL)GUANINE