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XD14

Product Name
XD14
CAS No.
1370888-71-3
Chemical Name
XD14
Synonyms
XD14;CS-2672;XD 14;XD-14;XD14, 10 mM in DMSO;XD14,Inhibitor,Epigenetic Reader Domain,XD-14,XD 14,inhibit;4-acetyl-N-[5-(diethylsulfamoyl)-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide;4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide;1H-Pyrrole-2-carboxamide, 4-acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-
CBNumber
CB53167334
Molecular Formula
C20H27N3O5S
Formula Weight
421.51
MOL File
1370888-71-3.mol
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XD14 Property

Density 
1.300±0.06 g/cm3(Predicted)
form 
Solid
pka
7.47±0.50(Predicted)
color 
Off-white to light yellow
InChI
InChI=1S/C20H27N3O5S/c1-6-15-18(13(5)24)12(4)21-19(15)20(26)22-16-11-14(9-10-17(16)25)29(27,28)23(7-2)8-3/h9-11,21,25H,6-8H2,1-5H3,(H,22,26)
InChIKey
DPBKLIVPNYGQQG-UHFFFAOYSA-N
SMILES
N1C(C)=C(C(C)=O)C(CC)=C1C(NC1=CC(S(N(CC)CC)(=O)=O)=CC=C1O)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A173550
Product name
4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
Packaging
50mg
Price
$770
Updated
2021/12/16
AK Scientific
Product number
SYN3048
Product name
XD14
Packaging
1mg
Price
$90
Updated
2021/12/16
Adipogen Life Sciences
Product number
SYN-3048-M005
Product name
XD14
Purity
≥95%
Packaging
5mg
Price
$130
Updated
2021/12/16
AK Scientific
Product number
SYN3048
Product name
XD14
Packaging
5mg
Price
$140
Updated
2021/12/16
AK Scientific
Product number
SYN3048
Product name
XD14
Packaging
50mg
Price
$670
Updated
2021/12/16
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XD14 Chemical Properties,Usage,Production

Uses

4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide is a bromodomain and extra-terminal (BET) inhibitor and exerts a strong inhibitory potential on the proliferation of specific leukemia cell lines.

IC 50

BRD2: 170 nM (Kd); BRD3: 380 nM (Kd); BRD4: 160 nM (Kd)

XD14 Preparation Products And Raw materials

Raw materials

Preparation Products

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XD14 Suppliers

ChemeGen
Tel
18818260767
Fax
QQ 3610331285
Email
2625930290@qq.com
Country
China
ProdList
6973
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58

1370888-71-3, XD14Related Search:


  • XD14
  • XD 14;XD-14
  • CS-2672
  • 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
  • XD14,Inhibitor,Epigenetic Reader Domain,XD-14,XD 14,inhibit
  • 1H-Pyrrole-2-carboxamide, 4-acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-
  • 4-acetyl-N-[5-(diethylsulfamoyl)-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
  • XD14, 10 mM in DMSO
  • 1370888-71-3