AUNP-12
- Product Name
- AUNP-12
- CAS No.
- 1353563-85-5
- Chemical Name
- AUNP-12
- Synonyms
- AUR 012;AUNP-12;NP-12 TFA;Aurigene-012;Aurigene NP-12;AURIGENE-012;AUR 012;L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
- CBNumber
- CB53168755
- Molecular Formula
- C142H226N40O48
- Formula Weight
- 3261.55
- MOL File
- 1353563-85-5.mol
AUNP-12 Property
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Water: Soluble
- form
- A solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 28053
- Product name
- AUNP-12
- Packaging
- 1mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 28053
- Product name
- AUNP-12
- Packaging
- 5mg
- Price
- $420
- Updated
- 2024/03/01
- Product number
- orb611287
- Product name
- AUNP-12
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1949.9
- Updated
- 2021/12/16
- Product number
- orb611287
- Product name
- AUNP-12
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3282.7
- Updated
- 2021/12/16
- Product number
- orb611287
- Product name
- AUNP-12
- Purity
- >98%
- Packaging
- 1g
- Price
- $5803.8
- Updated
- 2021/12/16
AUNP-12 Chemical Properties,Usage,Production
Biological Activity
AUNP-12 (Aur-012, Aurigene-012, Aurigene NP-12), a novel immune checkpoint modulator, is an inhibitor of PD-1 signaling pathway.
in vitro
In hPDL2-expressing HEK293 cells, AUNP-12 inhibited the binding of PD1 to PDL2 with EC50 of 0.72 nM; in hPDL1-expressing MDA-MB231 cells, in PBMC proliferation assay, EC50 was 0.41 nM.
target
| Target | Value |
| PD-L1 (Cell-free assay) |
AUNP-12 Preparation Products And Raw materials
Raw materials
Preparation Products
AUNP-12 Suppliers
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