ChemicalBook > CAS DataBase List > AUNP-12

AUNP-12

Product Name
AUNP-12
CAS No.
1353563-85-5
Chemical Name
AUNP-12
Synonyms
AUR 012;AUNP-12;NP-12 TFA;Aurigene-012;Aurigene NP-12;AURIGENE-012;AUR 012;L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
CBNumber
CB53168755
Molecular Formula
C142H226N40O48
Formula Weight
3261.55
MOL File
1353563-85-5.mol
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AUNP-12 Property

Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Water: Soluble
form 
A solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28053
Product name
AUNP-12
Packaging
1mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
28053
Product name
AUNP-12
Packaging
5mg
Price
$420
Updated
2024/03/01
Biorbyt Ltd
Product number
orb611287
Product name
AUNP-12
Purity
>98%
Packaging
100mg
Price
$1949.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611287
Product name
AUNP-12
Purity
>98%
Packaging
250mg
Price
$3282.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611287
Product name
AUNP-12
Purity
>98%
Packaging
1g
Price
$5803.8
Updated
2021/12/16
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AUNP-12 Chemical Properties,Usage,Production

Biological Activity

AUNP-12 (Aur-012, Aurigene-012, Aurigene NP-12), a novel immune checkpoint modulator, is an inhibitor of PD-1 signaling pathway.

in vitro

In hPDL2-expressing HEK293 cells, AUNP-12 inhibited the binding of PD1 to PDL2 with EC50 of 0.72 nM; in hPDL1-expressing MDA-MB231 cells, in PBMC proliferation assay, EC50 was 0.41 nM.

target

TargetValue
PD-L1
(Cell-free assay)

AUNP-12 Preparation Products And Raw materials

Raw materials

Preparation Products

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AUNP-12 Suppliers

China 39 United States 4 Global 43
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1353563-85-5, AUNP-12Related Search:

CHOLESTEROL ESTERASE

  • AUNP-12
  • AUR 012
  • Aurigene-012
  • AURIGENE-012;AUR 012
  • L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
  • Aurigene NP-12
  • NP-12 TFA
  • 1353563-85-5
  • C142H226N40O48