ChemicalBook > CAS DataBase List > 4-Oxo-TEMPO

4-Oxo-TEMPO

Product Name: 4-Oxo-TEMPO
CAS No.: 2896-70-0
Chemical Name: 4-Oxo-TEMPO
Synonyms: 4-OXO-TEMPO;TEMPONE;TANO;Tanone;ZJ-702;vitamin 702;4-Oxo-2,2,6,6;Tanone radical;4-Oxo Tempo (702);TIMTEC-BB SBB008633
CBNumber: CB5318995
Molecular Formula: C9H16NO2*
Formula Weight: 170.23
MOL File: 2896-70-0.mol

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4-Oxo-TEMPO Property

Melting point:: 33-38 °C
Boiling point:: 299.88°C (rough estimate)
Density: 1.0710 (rough estimate)
vapor pressure: 2.254Pa at 25℃
refractive index: 1.4640 (estimate)
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form: Needles, Crystals or Crystalline Powder
color: Orange
Water Solubility: Soluble in water (partly), acetone, DMSO, 100% ethanol, and diethylether. Insoluble in water.
BRN: 1818579
LogP: 0.28 at 22℃
CAS DataBase Reference: 2896-70-0(CAS DataBase Reference)
NIST Chemistry Reference: 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo-(2896-70-0)
EPA Substance Registry System: 1-Piperidinyloxy, 2,2,6,6-tetramethyl-4-oxo- (2896-70-0)

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Safety

Risk Statements: 36/37/38
Safety Statements: 24/25
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS: TN9200000
TSCA: Yes
HazardClass: 9
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 179485
Product name: 4-Oxo-TEMPO
Packaging: 1g
Price: $68
Updated: 2025/07/31

Sigma-Aldrich

Product number: 179485
Product name: 4-Oxo-TEMPO
Packaging: 5g
Price: $208
Updated: 2025/07/31

TCI Chemical

Product number: O0266
Product name: 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
Purity: >95.0%(GC)(T)
Packaging: 5g
Price: $101
Updated: 2025/07/31

TCI Chemical

Product number: O0266
Product name: 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
Purity: >95.0%(GC)(T)
Packaging: 25g
Price: $331
Updated: 2025/07/31

Cayman Chemical

Product number: 14877
Product name: TEMPONE
Purity: ≥98%
Packaging: 1g
Price: $32
Updated: 2024/03/01

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4-Oxo-TEMPO Chemical Properties,Usage,Production

Description

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.

Chemical Properties

Pink Needles

Uses

A spin label for ESR studies

Uses

Free-radical nitroxide spin probe typically used for:

Redox sources for anodes in lithium secondary batteries
Free-radical biological studies
Radical spin-trapping
Electron paramagnetic resonance studies
Polymer chemisty and synthesis applications

General Description

4-Oxo-TEMPO is formed by the reaction of 2,2,6,6-tetramethyl-4-piperidone (4-oxo-TMP) and ¹O₂. It is a stable paramagnetic product formed during the irradiation of TiO₂ in aqueous suspensions.

Flammability and Explosibility

Non flammable

References

[1] ADAM WU. Nitroxyl Radical Plus Hydroxylamine Pseudo Self-Exchange Reactions: Tunneling in Hydrogen Atom Transfer[J]. Journal of the American Chemical Society, 2009, 131 33: 11985-11997. DOI: 10.1021/ja904400d
[2] LUMATA L, MERRITT M, KHEMTONG C, et al. The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy?[J]. RSC Advances, 2012, 33: 12812-12817. DOI: 10.1039/c2ra21853d
[3] KINJAL PATEL. Acute antihypertensive action of nitroxides in the spontaneously hypertensive rat.[J]. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, 290 1: R37-43. DOI: 10.1152/ajpregu.00469.2005

4-Oxo-TEMPO Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Oxo-TEMPO manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 2896-70-0
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1000kg
Release date: 2025-06-13

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 2896-70-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Hubei Lidu New Material Technology Co., Ltd

Product: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY 2896-70-0
Price: US $0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 20tons
Release date: 2024-09-18

2896-70-0, 4-Oxo-TEMPORelated Search:

Triacetonediamine 2,2,6,6-Tetramethylpiperidine 1,1'-Carbonyldiimidazole 2,2,6,6-Tetramethyl-4-piperidinol PENICILLIN V 2,2,6,6-Tetramethylpiperidinooxy 4-Methylenepiperidine HCl 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine Carbonyl iron powder 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16-1-OXYL 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16,1-15N-1-OXYL 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 1-Acetyloxy-2,2,6,6-tetramethyl-4-oxopiperidine 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI- 1-Benzoyloxy-2,2,6,6-tetramethyl-4-oxopiperidine

4-Oxo-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical

4-OXO-TEMPO, FREE RADICAL 80+%

4-OXO-TEMPO, FREE RADICAL 99+%

4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOXY

4-Oxo-2,2,6,6-tetramethylpiperidine-1-oxyl(4-Oxo-TEMPO,freeradical)

4-Oxo-2,2,6,6

4-Oxo-2,2,6,6-trtramethyl-1-piperidi nyloxy,free radical

2,2,6,6-Tetramethyl-4-piperidone 1-oxyl, free radical

2,2,6,6-TETRAMETHYL-4-PIPERIDONE 1-OXYL

4-OXO-TEMPO

4-OXO-TEMPO, FREE RADICAL

4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY

4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINOOXY, FREE RADICAL

4-OXO-2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY

4-OXO-2,2,6,6-TETRAMETHYL-4-PIPERIDINYLOXY

4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL

2,2,6,6-TETRAMETHYLPIPERID-4-ONE-1-OXYL

4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical

4-OXO-TEMPO ---ORANGE SOLID, SPIN LABEL, PURITY 99%---

4-Oxo-2,2,6,6-tetramethylpiperidinooxy, 95%, free radical

(2,2,6,6-Tetramethyl-4-oxopiperidinooxy)radical

(2,2,6,6-Tetramethyl-4-oxopiperidinyloxy)radical

[(4-Oxo-2,2,6,6-tetramethylpiperidine-1-yl)oxy]radical

1-Piperidinyloxy radical, 2,2,6,6-tetramethyl-4-oxo-

2,2,6,6-tetramethyl-4-oxo-1-piperidinylox

2,2,6,6-tetramethyl-4-oxo-piperidin-1-oxyl

2,2,6,6-tetramethyl-4-oxo-piperidinoox

2,2,6,6-Tetramethyl-4-oxo-piperidinoxy

2,2,6,6-Tetramethyl-4-piperidone 1-nitroxide

2,2,6,6-Tetramethylpiperidone-1-oxyl

4-Oxo-2,2,6,6-tetramethylpiperidinooxyl

Piperidinooxy, 2,2,6,6-tetramethyl-4-oxo-

TANO

Tanone

Tanone radical

4-oxo-2,2,6,6-tetramethyl piperidone -1-oxyl

4-Oxo Tempo (702)

4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical(purified by sublimation)

4-Oxo TeMpo, free radical (4-Oxo-2,2,6,6-TetraMethyl-4-Piperidinyloxy, free radical)

ZJ-702

4-Oxo-2,2,6,6-tetraMethylpiperidinoxy (4-oxo-TeMpo)

4-Oxo-2,2,6,6-trtramethyl-1-piperidinyloxy

4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl&nbsp

Triacetoneamine nitroxide

Triacetoneamine N-oxyl

triacetoneamine-n-oxyl

TEMPONE

TIMTEC-BB SBB008633

1-OXYL-2,2,6,6-TETRAMETHYL-4-PIPERIDONE

2,2,6,6-TETRAMETHYL-4-OXO-1-PIPERIDINYLOXY

2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINOOXY

4-Oxo-2,2,6,6-tetramethylpiperidine1-OxylFreeRadical&gt

4-Oxo-tempo[4-Oxo-TEMPO]

4-Oxo-TEMPO, free radical, 96%,

1-(1H-1,3-BENZODIAZOL-2-YL)-1H-PYRAZOL-9-AMINE

Oxo-2,2,6,6-tetramethylpiperidinooxy

vitamin 702

Polycondensation inhibitor 702 / 4-Oxo-TEMPO