PD 158780

Product Name: PD 158780
Chemical Name: PD 158780
Synonyms: PD 158780;4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE
CBNumber: CB5326060
Molecular Formula: C14H12BrN5
Formula Weight: 330.18
MOL File: Mol file

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PD 158780 Property

storage temp.: -20°C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2615
Product name: PD 158780
Purity: ≥99%(HPLC)
Packaging: 10
Price: $212
Updated: 2021/12/16

Tocris

Product number: 2615
Product name: PD 158780
Purity: ≥99%(HPLC)
Packaging: 50
Price: $891
Updated: 2021/12/16

Usbiological

Product number: 256184
Product name: PD 158780
Packaging: 10mg
Price: $466
Updated: 2021/12/16

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PD 158780 Chemical Properties,Usage,Production

Uses

PD 158780 is a potent tyrosine kinase inhibitor of the epidermal growth factor receptor and has been shown to delay substantial growth of tumors in vivo tumor models.

Enzyme inhibitor

This photosensitive pyridopyrimidine (FW = 330.19 g/mol), known systematically as 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4- d]pyridimine, inhibits EPGFR (epidermal growth factor receptor) proteintyrosine kinase (IC50 = 8 pM). In addition, PD 158780 inhibits heregulinstimulated autophosphorylation in SK-BR-3 (IC50 = 49 nM) and MDA-MB- 453 (IC50 = 52 nM) breast carcinomas.

PD 158780 Preparation Products And Raw materials

Raw materials

Preparation Products

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PD 158780 Suppliers

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PD 158780Related Search:

PD168393 4-(4-FLUOROPHENYL)-2-(4-NITROPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE PD153035 HCl N-[2-[[4-(DIETHYLAMINO)BUTYL]AMINO-6-(3,5-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-N'-(1,1-DIMETHYLETHYL)UREA PD 166866

4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE

PD 158780